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Related Concept Videos

Blood Transfusion01:15

Blood Transfusion

606
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Typing01:10

Blood Typing

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target...
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Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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The ABO Blood Group01:12

The ABO Blood Group

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The ABO blood group system is a critical element of transfusion medicine, essential for determining blood compatibility in transfusions and organ transplants. It is based on specific antigens, or agglutinogens, present on the surface of red blood cells (RBCs) and corresponding antibodies, or agglutinins, in the blood plasma.
Antigens in the ABO Blood Group System
Antigens are substances that can trigger an immune response, leading to the production of antibodies. In the ABO blood group system,...
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Blood Types02:20

Blood Types

17.8K
Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...
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Rh Blood Group01:19

Rh Blood Group

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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
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Related Experiment Video

Updated: Jul 17, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
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How do we ensure a safe ABO recheck process?

Laura D Stephens1, Elizabeth S Allen1, Evan M Bloch2

  • 1University of California San Diego Health, La Jolla, California, USA.

Transfusion
|September 3, 2023
PubMed
Summary
This summary is machine-generated.

Properly labeling blood specimen tubes prevents wrong blood in tube (WBIT) errors, ensuring accurate ABO typing and safe transfusions. Various institutions use unique strategies to reduce these potentially fatal collection errors.

Keywords:
administrationregulatory and QAtransfusion service operations

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Area of Science:

  • Transfusion Medicine
  • Patient Safety
  • Clinical Laboratory Science

Background:

  • Accurate ABO typing relies on correctly labeled pretransfusion blood specimens.
  • Noncompliance in specimen collection can result in wrong blood in tube (WBIT) incidents, posing fatal risks.
  • Investigated current institutional practices to reduce WBIT errors and ensure accurate patient ABO typing.

Observation:

  • Institutions employ diverse methods to mitigate pretransfusion specimen misidentification.
  • Techniques include TM laboratory-generated orders, dedicated collection tubes from TM services, and barcoding for electronic patient identification.
  • Combined strategies are used based on specimen collection location or service line.

Findings:

  • Multiple institutions utilize specific protocols to prevent misidentified pretransfusion specimens.
  • Key strategies involve centralized order generation, exclusive tube distribution, and advanced identification technologies.
  • The choice of mitigation strategy often depends on institutional infrastructure and specific clinical settings.

Implications:

  • Sharing WBIT mitigation strategies can guide transfusion medicine (TM) services in adopting effective practices.
  • Continuous monitoring and mitigation of specimen misidentification are crucial for sustained transfusion safety.
  • Implementing robust procedures enhances patient safety and reduces the risk of transfusion-related errors.