Vibratory perception threshold in patients with mild multiple sclerosis

The vibratory perception threshold (VPT) was measured bilaterally on both the upper and lower extremity in 69 patients with mild multiple sclerosis. In the case of the lower extremities the VPT measurements were closely correlated with qualitative vibratory perception measurements performed with a tuning fork; in the upper extremities the association was weak. The VPT was abnormal at least in one extremity in 38% of the patients. Quantitative VPT measurement seem to be a suitable technique for the detection of sensory symptoms of central origin.