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Nanobody-based bispecific T-cell engager (Nb-BiTE): a new platform for enhanced T-cell immunotherapy

Xiao-Mei Yang1, Xuan-Dong Lin1, Wei Shi1

  • 1Guangxi Key Laboratory of Nanobody Research, Guangxi Nanobody Engineering Research Center, College of Stomatology, Hospital of Stomatology, Laboratory Animal Center, School of Basic Medical Science, Pharmaceutical College, Guangxi Medical University, Nanning City, Guangxi, 530021, P. R. China.

Signal Transduction and Targeted Therapy
|September 3, 2023
PubMed
Abstract

No abstract available in PubMed .

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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