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Upadacitinib in nail psoriasis: a case report
Na Wang1,2, Qing Yang1,2, Yongxia Liu1,2
1Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Upadacitinib shows promise for treating severe nail psoriasis, a challenging condition. This JAK inhibitor effectively improved nail symptoms in a patient, suggesting potential for similar cases.
Area of Science:
- Dermatology
- Immunology
- Rheumatology
Background:
- Nail psoriasis affects a significant portion of patients with psoriasis and psoriatic arthritis (PsA).
- The exact mechanisms driving nail psoriasis are not fully understood, but involve similar inflammatory pathways as skin lesions.
- Current treatments for nail psoriasis are often challenging and require personalized approaches.
Conclusions:
- Upadacitinib demonstrates potential as a valuable treatment option for severe nail psoriasis.
- Further research into JAK inhibitors for nail psoriasis is warranted.
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The main components of a nail include the following.
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