Related Experiment Video
Updated: Jul 17, 2025

Author Spotlight: Advancing Research on Candida albicans Biofilm-Associated Prosthetic Joint Infections
Published on: February 2, 2024
Kocuria rhizophila prosthetic hip joint infection
Timothy McAleese1,2, Aathir Ahmed1,2, Mark Berney2
1RCSI University of Medicine and Health Sciences, 123 St Stephen's Green, Dublin, D02 YN77, Ireland.
Abstract:
We present the first case report of prosthetic joint infection (PJI) caused by Kocuria rhizophila. Our patient is a 74-year-old male who underwent primary total hip replacement for right hip pain. His recovery was uneventful until 6 weeks postoperatively when he presented to his routine outpatient appointment with significant erythema, swelling, and tenderness over his right hip wound. Based on the acuity of his symptoms and the radiological findings, it was determined that the patient should undergo debridement, antibiotics, and implant retention (DAIR procedure). A consensus decision was also made at our PJI multidisciplinary meeting to treat him with 12 weeks of IV antibiotics. After completing this 12 weeks course of IV Vancomycin, his inflammatory markers returned to normal limits. At 6 months follow-up, our patient was mobilizing independently without any signs of infection recurrence. His radiographs showed the implant was in a satisfactory position with no evidence of loosening. This case adds to an emerging body of literature describing invasive infections associated with Kocuria species. We have demonstrated the effectiveness of managing this condition with debridement, implant retention, and IV Vancomycin therapy for 12 weeks.
Insights
This case report details the first prosthetic joint infection (PJI) caused by Kocuria rhizophila. Effective treatment involved debridement, antibiotics, and implant retention (DAIR) with Vancomycin.
Area of Science:
- Infectious Diseases
- Orthopedic Surgery
- Microbiology
Background:
- Prosthetic joint infection (PJI) is a serious complication following joint replacement surgery.
- Kocuria species are increasingly recognized as opportunistic pathogens.
- This report focuses on a rare PJI caused by Kocuria rhizophila.
Observation:
- A 74-year-old male presented with signs of infection 6 weeks after total hip replacement.
- Symptoms included erythema, swelling, and tenderness at the surgical site.
- Radiological findings indicated a potential PJI.
Findings:
- Kocuria rhizophila was identified as the causative agent of the prosthetic joint infection.
- The patient was successfully treated with debridement, antibiotics, and implant retention (DAIR) procedure.
- A 12-week course of intravenous Vancomycin led to normalization of inflammatory markers and clinical recovery.
Implications:
- This case highlights Kocuria rhizophila as a potential cause of PJI.
- It demonstrates the efficacy of the DAIR procedure and prolonged Vancomycin therapy for such infections.
- Further research into Kocuria species' role in invasive infections is warranted.

