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Outcomes of out-of-hospital cardiac arrest in Ireland 2012-2020: Protocol for an observational study
Tomás Barry1, Alice Kasemiire2, Martin Quinn3
1UCD School of Medicine, University College Dublin, Dublin, Leinster, D04 V1W8, Ireland.
Insights
Out-of-hospital cardiac arrest survival in Ireland remains low. This study analyzes trends from 2012-2020 to identify predictors of bystander CPR, defibrillation, and survival, assessing the impact of health system developments.
Area of Science:
- Emergency Medicine
- Public Health
- Cardiovascular Research
Background:
- Out-of-hospital cardiac arrest (OHCA) is a significant cause of preventable death in Ireland, with survival rates lower than the European average.
- The Irish Out-of-Hospital Cardiac Registry (OHCAR) collects data on OHCA events where emergency services attempted resuscitation.
- The period 2012-2020 saw several Irish health system developments relevant to OHCA care.
Purpose of the Study:
- To summarize key trends in OHCA incidence, care, and outcomes in Ireland from 2012-2020 using OHCAR data.
- To model predictors of bystander CPR, bystander defibrillation, and survival to hospital discharge.
- To investigate if health system developments influenced OHCA care processes and survival rates.
Main Methods:
- Observational study utilizing prospectively gathered OHCAR data from 2012-2020.
- Descriptive summaries and graphical displays to evaluate key trends in OHCA data.
- Multivariable logistic regression to model predictors and assess the impact of system developments and the COVID-19 pandemic on outcomes.
Main Results:
- Analysis of temporal trends in OHCA incidence, bystander interventions, and survival.
- Identification of key predictors for bystander CPR, bystander defibrillation, and survival to hospital discharge.
- Evaluation of the association between health system developments and changes in OHCA outcomes.
Conclusions:
- Understanding temporal trends in OHCA care and outcomes is crucial for improving survival rates.
- Findings will inform optimization of future health system developments for OHCA management in Ireland and internationally.
- The study provides insights into the effectiveness of interventions and system changes on OHCA survival.
Background:
Out-of-hospital cardiac arrest (OHCA) is a leading cause of preventable mortality that now affects almost 3,000 people each year in Ireland. Survival is low at 6-7%, compared to a European average of 8%. The Irish Out-of-Hospital Cardiac Registry (OHCAR) prospectively gathers data on all OHCA in Ireland where emergency medical services attempted resuscitation.The Irish health system has undergone several developments that are relevant to OHCA care in the period 2012-2020. OHCAR data provides a means of exploring temporal trends in OHCA incidence, care, and outcomes over time. It also provides a means of exploring whether system developments were associated with a change in key outcomes.This research aims to summarise key trends in available OHCAR data from the period 2012 - 2020, to explore and model predictors of bystander CPR, bystander defibrillation, and survival, and to explore the hypothesis that significant system level temporal developments were associated with improvements in these outcomes.
Methods:
The following protocol sets out the relevant background and research approach for an observational study that will address the above aims. Key trends in available OHCAR data (2012 - 2020) will be described and evaluated using descriptive summaries and graphical displays. Multivariable logistic regression will be used to model predictors of 'bystander CPR', 'bystander defibrillation' and 'survival to hospital discharge' and to explore the effects (if any) of system level developments in 2015/2016 and the COVID-19 pandemic (2020) on these outcomes.
Discussion:
The findings of this research will be used to understand temporal trends in the care processes and outcomes for OHCA in Ireland over the period 2012-2020. The results can further be used to optimise future health system developments for OHCA in both Ireland and internationally.
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