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Updated: Jul 17, 2025

RNAscope for In situ Detection of Transcriptionally Active Human Papillomavirus in Head and Neck Squamous Cell Carcinoma
Published on: March 11, 2014
Non-human papillomavirus penile squamous cell carcinoma with unusual coral-like polymorphic lesion
Sherryn Sherryn1, I Putu Gde Sanjaya2, Luh Dewi Rahayu3
1Department of Clinical Medicine, Universitas Cenderawasih, Jayapura, Papua, Indonesia.
Abstract:
Penile cancer is a rare malignancy of the male genital system. Approximately 98% of penile cancer corresponds to squamous cell carcinoma (SCC), with further morphological and molecular classification into human papillomavirus (HPV) dependent and non-HPV SCC. Compared to HPV-induced SCC, non-HPV SCC appeared to have a worse prognosis. Here, we present a case of an uncircumcised male with an unusual coral-like polymorphic lesion, and confirmed histopathology of well-differentiated non-HPV penile SCC with rapid growth progression.
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