Related Experiment Video
Updated: Jul 17, 2025
14:58
Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
9.7K
Cerebrovascular Fibromuscular Dysplasia - A Practical Review
Praveen Kesav1, Divya Manesh Raj2, Seby John3
1Department of Neurology, Neurological Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates.
Vascular Health and Risk Management
|September 4, 2023
Summary
Fibromuscular dysplasia (FMD) affects medium arteries, particularly in young to middle-aged women. Cerebrovascular FMD (C-FMD) is common, presenting with headaches, stroke, or dissection.
Area of Science:
- Vascular Medicine
- Neurology
- Genetics
Background:
- Fibromuscular dysplasia (FMD) is a rare, non-inflammatory arteriopathy affecting medium-sized arteries.
- It predominantly impacts young to middle-aged females and is a systemic condition.
- Cerebrovascular FMD (C-FMD) is increasingly recognized, with prevalence similar to renovascular FMD.
Purpose of the Study:
- To provide a comprehensive and updated overview of cerebrovascular FMD (C-FMD).
- To cover epidemiology, clinical presentation, etiology, diagnosis, and management of C-FMD.
- To synthesize recent data from international FMD cohorts.
Main Methods:
- Review of recent international FMD cohort data.
- Synthesis of existing literature on C-FMD.
- Comprehensive overview of C-FMD aspects.
Main Results:
- C-FMD commonly involves extracranial carotid and vertebral arteries.
- Clinical presentations range from headaches and tinnitus to severe events like stroke and hemorrhage.
- Associated pathologies include cervical artery dissection and intracranial aneurysms.
Conclusions:
- C-FMD is a significant cerebrovascular condition with diverse presentations.
- Understanding of C-FMD has improved due to recent international data.
- This review offers an updated perspective on C-FMD epidemiology, diagnosis, and management.
