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Thermal Measurement Techniques in Analytical Microfluidic Devices
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Hydrogel Micropillar Array for Temperature Sensing in Fluid.

Sang-Woo Seo1, Youngsik Song1, Nafis Mustakim1

  • 1Department of Electrical Engineering, City College of City University of New York, New York, NY 10031 USA.

IEEE Sensors Journal
|September 4, 2023
PubMed
Summary
This summary is machine-generated.

We developed a micron-sized hydrogel pillar array for precise local temperature sensing and control. This technology enables dynamic temperature mapping and actuation in liquid environments, ideal for biological applications.

Keywords:
Au nanorodsmicro-pillar arrayp-NIPAAm hydrogelphotothermal actuationtemperature sensing

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Area of Science:

  • Materials Science
  • Biotechnology
  • Microfluidics

Background:

  • Localized temperature control is crucial for biological systems.
  • Existing methods lack micron-scale precision for sensing and actuation.
  • Hydrogels offer tunable thermal properties.

Purpose of the Study:

  • To develop a micron-sized hydrogel pillar array for localized temperature sensing and actuation.
  • To investigate the temperature-dependent volume change of poly N-isopropyl acrylamide (p-NIPAAm) hydrogels.
  • To demonstrate spatiotemporal temperature mapping and modulation using near-infrared (NIR) light.

Main Methods:

  • Fabrication of p-NIPAAm hydrogel pillar arrays using soft lithography.
  • Embedding gold nanorods within hydrogel pillars for light-induced heating.
  • Utilizing NIR light to induce localized heating and monitor pillar volume changes.
  • Copolymerization of N-isopropyl acrylamide with acrylamide (AAM) to adjust the low critical solution temperature (LCST).

Main Results:

  • Hydrogel pillars exhibited sensitive volume transitions near their LCST.
  • LCST was tunable by copolymerization with AAM.
  • Spatiotemporal temperature mapping in water was achieved by monitoring pillar volume changes.
  • Actuation via localized NIR light heating was successfully demonstrated.

Conclusions:

  • The micron-sized hydrogel pillar array serves as a sensitive temperature probe and actuator.
  • The system allows for high-resolution, localized temperature modulation and mapping in liquids.
  • This technology holds significant potential for applications in biological systems requiring precise thermal control.