Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantitative proteomics analysis of cerebrospinal fluid reveals putative protein biomarkers for canine non-infectious meningoencephalomyelitis.

Veterinary journal (London, England : 1997)·2024
Same author

Comparative study of select biochemical markers in cerebrospinal fluid of healthy dogs before and after treatment with nutraceuticals.

Veterinary clinical pathology·2014
Same author

Short communication: cerebrospinal fluid lactate and pyruvate concentrations and ratio in healthy adult dogs.

The Veterinary record·2013
Same author

Oligodendroglial gliomatosis cerebri in a poodle.

Veterinary and comparative oncology·2010
Same author

[Arterial embolization to control acute intraoperative bleeding].

Revista espanola de anestesiologia y reanimacion·2009
Same author

Presumed primary uveal melanoma with brain extension in a dog.

The Journal of small animal practice·2009

Related Experiment Video

Updated: Jul 17, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

3.0K

Comparing optic nerve head parameters in two Spanish dog breeds using digital planimetry.

C Merchán1, P Mesa1, E M Martín-Suárez1

  • 1Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Córdoba University, Campus de Rabanales Crt Madrid-Cádiz km 396, 14014 Córdoba, Spain.

Research in Veterinary Science
|September 4, 2023
PubMed
Summary

Optic nerve head (ONH) measurements in dogs vary significantly by breed and age. Digital planimetry (DP) offers a reliable method for assessing these canine ONH parameters, aiding in clinical interpretation.

Keywords:
BreedDogMorphometric analysisOcular fundusOptic disc

More Related Videos

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.4K
Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research
10:10

Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research

Published on: November 2, 2018

9.3K

Related Experiment Videos

Last Updated: Jul 17, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
07:44

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

3.0K
Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential
07:11

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

6.4K
Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research
10:10

Ultrahigh Resolution Mouse Optical Coherence Tomography to Aid Intraocular Injection in Retinal Gene Therapy Research

Published on: November 2, 2018

9.3K

Area of Science:

  • Veterinary Ophthalmology
  • Comparative Anatomy
  • Ophthalmic Imaging

Background:

  • Optic disc variations in dogs complicate lesion interpretation due to a lack of reference patterns.
  • Myelination significantly influences optic disc size, shape, and color in canine eyes.

Purpose of the Study:

  • To compare optic nerve head (ONH) parameters between Spanish Greyhounds (SG) and Spanish Water Dogs (SWD) using digital planimetry (DP).
  • To evaluate the influence of age and breed on ONH morphology in dogs.
  • To assess the reliability of DP for ONH measurements in canine ophthalmology.

Main Methods:

  • Digital planimetry (DP) was employed to calculate ONH parameters including vertical/horizontal diameters, area, circularity, and regional proportions (top/bottom height).
  • Image analysis software was used for measurements, with comparisons made between two pure breeds: SG and SWD.
  • Linear and multiple regression analyses were performed to determine the impact of age and breed on ONH parameters.

Main Results:

  • Significant differences in ONH height, width, area, and circularity were found between SWD and SG breeds.
  • Age was a significant factor influencing mean disc height, width, area, and circularity (R² values ranging from 0.243 to 0.310).
  • A multiple regression model incorporating age and breed accurately predicted ONH dimensions (R² values up to 0.742).
  • High concordance was observed between measurements by experienced and novice researchers, and between manual and software-derived data.

Conclusions:

  • Digital planimetry (DP) provides a reliable and easily executable method for measuring canine optic nerve head (ONH) parameters, even for novice operators.
  • Breed and age are critical factors influencing canine ONH morphology, necessitating breed-specific reference ranges.
  • These findings have potential clinical value for diagnosing and monitoring canine eye conditions, though further research is needed due to inherent variability.