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Updated: Jul 17, 2025
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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Exploring Heterogeneity in perinatal depression: a comprehensive review.
Ahmed Waqas1, Mahnoor Nadeem2, Atif Rahman3
1Department of Primary Care & Mental Health, Institute of Population Health, University of Liverpool, Liverpool, UK. ahmed.waqas@liverpool.ac.uk.
BMC Psychiatry
|September 4, 2023
Summary
Perinatal depression (PND) is not a single condition but a heterogeneous disorder with varied phenotypes. Recognizing this heterogeneity is crucial for effective research, public health, and clinical interventions for maternal mental health.
Area of Science:
- Perinatal mental health
- Psychiatry
- Epidemiology
Background:
- Perinatal depression (PND) significantly impacts maternal morbidity and infant development globally.
- Recent research suggests PND is a heterogeneous condition with diverse phenotypes, challenging traditional diagnostic models.
- Understanding PND heterogeneity is vital for advancing etiological research and intervention development.
Conclusions:
- PND is a heterogeneous condition requiring tailored approaches.
- Findings have significant implications for public health policy and clinical practice in perinatal mental healthcare.
- Recommendations are provided to enhance screening, diagnosis, and treatment strategies for PND.
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