Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Infertility in Males01:23

Infertility in Males

295
Male infertility affects millions of couples worldwide, arising from various factors that impact different stages of the reproductive process. An endocrine imbalance resulting from conditions like hypogonadism, Klinefelter syndrome, or pituitary disorders can disrupt hormone levels and reduce sperm production. Testicular defects, such as tumors, cryptorchidism, atrophic testes, abnormal sperm morphology, and low sperm count or motility, may arise due to genetic factors, structural...
295
Infertility in Females01:28

Infertility in Females

348
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
348
Role of Reduced Coenzymes NADH and FADH₂01:29

Role of Reduced Coenzymes NADH and FADH₂

11.9K
The energy released from the breakdown of the chemical bonds within nutrients can be stored either through the reduction of electron carriers or in the bonds of adenosine triphosphate (ATP). In living systems, a small class of compounds functions as mobile electron carriers, molecules that bind to and shuttle high-energy electrons between compounds in pathways. The principal electron carriers that will be considered originate from the B vitamin group and are derivatives of nucleotides; they are...
11.9K
Testosterone: Functions and Regulation01:26

Testosterone: Functions and Regulation

740
The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
740
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

435
The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
435
Cofactors and Coenzymes01:24

Cofactors and Coenzymes

11.1K
Enzymes are proteins made of amino acids. The functional group of each constituent amino acid catalyzes a wide variety of chemical reactions via ionic interactions or acid-base reactions. However, amino acids cannot catalyze oxidation-reduction and group transfer reactions and need to be aided by non-protein components called cofactors. Cofactors are also referred to as the chemical teeth of an enzyme.
Cofactors can be metallic ions or organic molecules called coenzymes. These types of helper...
11.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unlocking Success: The Optimal Gonadotrophin Starting Point for Luteal-Phase Stimulation in IVF Patients with Normal Responses.

International journal of women's health·2025
Same author

Global Burden of Cardiovascular Disease from 1990 to 2019 Attributable to Dietary Factors.

The Journal of nutrition·2023
Same author

Progress in the application of patch materials in cardiovascular surgery.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences·2023
Same author

Purinergic receptor P2X7 contributes to abdominal aortic aneurysm development via modulating macrophage pyroptosis and inflammation.

Translational research : the journal of laboratory and clinical medicine·2023
Same author

Evaluation of the effectiveness and safety of a multi-faceted computerized antimicrobial stewardship intervention in surgical settings: A single-centre cluster-randomized controlled trial.

International journal of antimicrobial agents·2023
Same author

Expression characteristics of Hsd3b7 in the gonads of Paralichthys olivaceus.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology·2023

Related Experiment Video

Updated: Jul 17, 2025

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools
05:27

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools

Published on: July 20, 2022

1.9K

Coenzyme Q10 Stimulate Reproductive Vatality.

Xinyu Nie1,2, Xinru Dong1,2, Yuge Hu1,2

  • 1Obstetrics and Gynecology Center, First Hospital of Jilin University, Changchun, Jilin, People's Republic of China.

Drug Design, Development and Therapy
|September 5, 2023
PubMed
Summary

Coenzyme Q10 (CoQ10) may improve female fertility by reducing oxidative stress and enhancing mitochondrial function. This review explores its potential therapeutic benefits for reproductive disorders.

Keywords:
coenzyme Q10endometriosisoocyteoxidative stressreactive oxygen speciesreproductive

More Related Videos

Mitochondrial Respiration Quantification in Yeast Whole Cells
07:15

Mitochondrial Respiration Quantification in Yeast Whole Cells

Published on: November 8, 2024

597
Assessment of Open Probability of the Mitochondrial Permeability Transition Pore in the Setting of Coenzyme Q Excess
07:35

Assessment of Open Probability of the Mitochondrial Permeability Transition Pore in the Setting of Coenzyme Q Excess

Published on: June 1, 2022

2.3K

Related Experiment Videos

Last Updated: Jul 17, 2025

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools
05:27

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools

Published on: July 20, 2022

1.9K
Mitochondrial Respiration Quantification in Yeast Whole Cells
07:15

Mitochondrial Respiration Quantification in Yeast Whole Cells

Published on: November 8, 2024

597
Assessment of Open Probability of the Mitochondrial Permeability Transition Pore in the Setting of Coenzyme Q Excess
07:35

Assessment of Open Probability of the Mitochondrial Permeability Transition Pore in the Setting of Coenzyme Q Excess

Published on: June 1, 2022

2.3K

Area of Science:

  • Reproductive Biology
  • Mitochondrial Medicine
  • Oxidative Stress Research

Background:

  • Female infertility and recurrent spontaneous abortion are significant clinical challenges.
  • Current treatments are insufficient for some patients, leading to diagnoses of unexplained infertility.
  • Coenzyme Q10 (CoQ10) is vital for mitochondrial energy production and acts as an antioxidant.

Purpose of the Study:

  • To systematically review the multifaceted effects of CoQ10 in female reproductive disorders.
  • To investigate the mechanisms underlying CoQ10's therapeutic potential.
  • To provide a reference for future research on CoQ10 as an adjuvant therapy.

Main Methods:

  • Literature review of studies on CoQ10 and female reproductive health.
  • Analysis of CoQ10's roles in mitochondrial function, oxidative stress, and inflammation.
  • Examination of CoQ10's impact on ovarian function, oocyte quality, and embryonic development.

Main Results:

  • CoQ10 demonstrates antioxidant and anti-inflammatory properties.
  • It enhances mitochondrial activity, crucial for cellular energy production.
  • Emerging evidence suggests CoQ10 may improve oocyte quality, fertilization, and embryonic development.

Conclusions:

  • CoQ10 exhibits pleiotropic effects beneficial for female reproductive health.
  • Its antioxidant and mitochondrial-enhancing capabilities offer therapeutic potential for infertility and pregnancy maintenance.
  • Further research is warranted to fully elucidate CoQ10's mechanisms and clinical applications in female reproductive disorders.