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Updated: Jul 17, 2025

Trans-Tympanic Drug Delivery for the Treatment of Ototoxicity
Published on: March 16, 2018
Drug Shortages and Otolaryngology
Antoinette R Esce1, Andrew G Shuman2,3
1Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, University of New Mexico Health Sciences Center, Albuquerque, New Mexico, USA.
Abstract:
Every year in the United States, hundreds of shortages of life-saving, essential drugs impact patients and health care workers. While otolaryngologists may be shielded from these relative to other specialties, there is still a significant clinical impact with potentially dangerous consequences. Shortages of local anesthetics lead to increased costs, labor demands, and risk of medical errors. Shortages of cisplatin and carboplatin, workhorses in head and neck oncology, may leave patients without proven alternative therapies. The economic and geopolitical challenges that provoke these shortages are well described. So too are potential solutions at the national, regional, and local levels. Otolaryngologists have a responsibility to contribute to coordinated responses to drug shortages to protect and advocate for their current and future patients.
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