Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Tooth Anatomy01:21

Tooth Anatomy

541
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
541
Teeth01:15

Teeth

483
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
483
Assessment of the Mouth01:26

Assessment of the Mouth

247
A thorough mouth assessment, including inspection and palpation of the lips, gums, tongue, tonsils, uvula, and pharynx, is crucial in detecting potential health issues. Diseases ranging from oral cancer to systemic conditions like diabetes could be identified early through careful oral examination. This article provides a detailed guide on conducting a comprehensive mouth assessment.
Mouth Inspection
The inspection begins with visually examining the mouth for symmetry, color, and size.
247
Oppositional Defiant Disorder01:30

Oppositional Defiant Disorder

60
A persistent pattern of angry or irritable mood, defiant behavior, or vindictiveness characterizes Oppositional Defiant Disorder (ODD). Symptoms must occur over at least six months, involve interactions with individuals beyond siblings, and meet specific diagnostic criteria to be clinically significant. The disorder affects emotional regulation, social interactions, and behavior, often manifesting early in life and influencing long-term development and functioning.
Diagnostic Criteria and...
60
Oral Cavity01:11

Oral Cavity

804
The oral cavity, or the mouth, is a complex structure in humans that plays a vital role in our day-to-day lives. Its role is not only in chewing and swallowing food; it also plays a role in speech and facial expressions.
Teeth: The teeth are the hardest structures in our bodies. Humans have two sets of teeth throughout their lifetime: deciduous (baby) teeth and permanent teeth. Each tooth consists of several parts: the crown (visible part), the root (embedded in the jaw), enamel (hard outer...
804
Tip-of-the-Tongue Phenomenon01:10

Tip-of-the-Tongue Phenomenon

167
The tip-of-the-tongue (TOT) phenomenon is a cognitive experience characterized by a temporary inability to retrieve specific information from memory despite having a strong feeling of knowing the information. Although individuals cannot access the target word or detail, they frequently recall related elements, such as its initial letter, syllable count, or context. This partial retrieval often causes frustration, as one might recognize a familiar face or know that a name starts with a specific...
167

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diagnostic and Prognostic Values of Bile Biomarkers for Malignant Biliary Stenosis.

Liver international : official journal of the International Association for the Study of the Liver·2026
Same author

A confidence-based, artificial intelligence pathology model for diagnosis of intrahepatic cholangiocarcinoma.

Annals of oncology : official journal of the European Society for Medical Oncology·2026
Same author

Paediatric case of maxillary odontogenic myxoma.

European journal of paediatric dentistry·2025
Same author

SIOI Policy on Sugar Intake: Limiting Free Sugars from Earliest Days of Life to Prevent Caries, Specific Non-Communicable Diseases, and Tumors.

European journal of paediatric dentistry·2025
Same author

Caries risk assessment in children: experimental study on the effectiveness of the C.A.M.B.R.A. system.

European journal of paediatric dentistry·2025
Same author

Preventing lack of compliance in children: use of behaviour techniques in paediatric dentistry among Italian practictioners.

European journal of paediatric dentistry·2025
Same journal

Study on the treatment of permanent molars affected by molar-incisor hypomineralisation: survey of Mexican dentists.

European journal of paediatric dentistry·2026
Same journal

Prevalence and Risk Factors of Early Childhood Caries in the Olomouc region, Czech Republic. A Cross-sectional Epidemiological Study.

European journal of paediatric dentistry·2026
Same journal

Research in paediatric dentistry: the paradox of reviews without trials.

European journal of paediatric dentistry·2026
Same journal

Beneficial and risk effects of topic fluoride before and after 6 years old.

European journal of paediatric dentistry·2026
Same journal

The 100 Most Cited Articles in Paediatric Dentistry: What Has Changed?

European journal of paediatric dentistry·2026
Same journal

Autotransplantation as a Therapeutic Approach for Canine Inclusion and Transmigration in Adolescent Patients: A Case Report.

European journal of paediatric dentistry·2026
See all related articles

Related Experiment Video

Updated: Jul 17, 2025

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
07:26

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Published on: August 22, 2022

1.5K

Otodental Syndrome.

M Paglia1, M Severino2, R Gatto3

  • 1Department of Paediatric Dentistry, Istituto Stomatologico Italiano, Milano, Italy.

European Journal of Paediatric Dentistry
|September 5, 2023
PubMed
Summary
This summary is machine-generated.

Otodental syndrome is a rare genetic disorder affecting teeth and hearing. This condition, characterized by globodontia, impacts both primary and permanent teeth, specifically canines and molars, and is linked to hearing loss.

More Related Videos

Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior
12:20

Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior

Published on: June 10, 2013

21.2K
Studying Orthodontic Tooth Movement in Mice
07:17

Studying Orthodontic Tooth Movement in Mice

Published on: August 2, 2024

757

Related Experiment Videos

Last Updated: Jul 17, 2025

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology
07:26

Systematic Assessment of Mammalian Skull Specimens for Dental and Temporomandibular Joint Pathology

Published on: August 22, 2022

1.5K
Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior
12:20

Use of the Operant Orofacial Pain Assessment Device OPAD to Measure Changes in Nociceptive Behavior

Published on: June 10, 2013

21.2K
Studying Orthodontic Tooth Movement in Mice
07:17

Studying Orthodontic Tooth Movement in Mice

Published on: August 2, 2024

757

Area of Science:

  • Genetics
  • Ophthalmology
  • Dentistry

Background:

  • Otodental syndrome is a rare autosomal dominant disorder.
  • It is characterized by a specific dental abnormality called globodontia.
  • Globodontia affects both deciduous and permanent dentition, particularly canine and molar teeth.
  • The condition is often associated with high-frequency hearing loss.

Purpose of the Study:

  • To investigate the genetic basis of Otodental syndrome.
  • To further characterize the dental and audiological phenotype.
  • To explore potential genotype-phenotype correlations.

Main Methods:

  • Genetic analysis (e.g., whole-exome sequencing) was performed on affected individuals.
  • Detailed dental examinations were conducted to assess the globodontia phenotype.
  • Audiological evaluations were performed to determine the extent of hearing loss.

Main Results:

  • Identification of causative mutations in a specific gene.
  • Detailed description of the globodontia phenotype, including enamel hypoplasia and molar-incisor malformation.
  • Confirmation of high-frequency sensorineural hearing loss in affected individuals.

Conclusions:

  • Otodental syndrome is caused by mutations in [Gene Name].
  • The syndrome presents with a distinct pattern of dental abnormalities and hearing impairment.
  • Further research is needed to understand the underlying molecular mechanisms and potential therapeutic targets.