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Related Concept Videos

Knee Joint01:23

Knee Joint

1.9K
The knee joint is the most complicated joint in the body. It consists of three articulations– two tibiofemoral and one patellofemoral. As is characteristic of synovial joints, the knee joint has a thin articular capsule that partially surrounds this joint cavity. Additionally, several ligaments, muscles, and cartilaginous structures support the movement of the knee.
A total of seven ligaments support the knee joint. The patellar ligament, which is also attached to the quadriceps femoris...
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Bones of the Lower Limb: Femur and Patella01:16

Bones of the Lower Limb: Femur and Patella

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The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the...
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Updated: Jul 17, 2025

Tissue Collection and RNA Extraction from the Human Osteoarthritic Knee Joint
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Knee Osteonecrosis After SARS-CoV-2 Virus Infection.

Ana Muñoz García1, Florencio Jiménez Martín, David Hernández Herrero

  • 1From the La Paz University Hospital, Madrid, Spain.

American Journal of Physical Medicine & Rehabilitation
|September 5, 2023
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Summary

COVID-19 infection can lead to osteonecrosis due to various factors including coagulopathy and corticosteroid treatment. Early diagnosis of this knee osteonecrosis is crucial for better patient outcomes.

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Area of Science:

  • Orthopedics
  • Infectious Diseases
  • Radiology

Background:

  • Osteonecrosis is a complex condition potentially linked to COVID-19 infection.
  • Contributing factors include viral coagulopathy, genetic predispositions, and corticosteroid therapies.
  • Challenges in diagnosis arise from varied clinical presentations.

Observation:

  • A case report details knee osteonecrosis in a female patient with no prior knee issues.
  • Diagnosis was confirmed via magnetic resonance imaging.
  • The patient had been hospitalized for SARS-CoV-2 pneumonia requiring high-dose corticosteroids.

Findings:

  • The patient developed osteonecrosis months after SARS-CoV-2 pneumonia.
  • Magnetic resonance imaging confirmed osteonecrosis in the knee.
  • No pre-existing knee pathology was noted on initial imaging.

Implications:

  • This case highlights a potential complication of severe COVID-19 and its treatment.
  • Prompt diagnosis of osteonecrosis is vital to mitigate progression and surgical intervention.
  • Further research into the mechanisms linking COVID-19, corticosteroids, and osteonecrosis is warranted.