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Hemodynamic Precision in the Neonatal Intensive Care Unit using Targeted Neonatal Echocardiography
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Echocardiographic Findings in Children with Multisystem Inflammatory Syndrome from Initial Presentation to the First

Muhammet Bulut1, Filiz Ekici1, Tuğçe Tural Kara2

  • 1Department of Pediatric Cardiology, Akdeniz University Faculty of Medicine, Antalya, Turkey.

Turkish Archives of Pediatrics
|September 6, 2023
PubMed

Insights

Multisystem inflammatory syndrome in children (MIS-C) linked to COVID-19 often causes temporary heart issues. Most children recover quickly, but long-term monitoring of coronary arteries is recommended.

Area of Science:

  • Pediatrics
  • Cardiology
  • Infectious Diseases

Background:

  • Multisystem inflammatory syndrome (MIS) in children is a serious condition linked to SARS-CoV-2 infection.
  • Cardiovascular involvement is a significant concern in pediatric MIS cases.

Purpose of the Study:

  • To assess clinical and echocardiographic features of MIS-C in children.
  • To determine early and mid-term cardiovascular outcomes in pediatric MIS-C patients.

Main Methods:

  • Retrospective evaluation of 38 children diagnosed with MIS-C between November 2020 and November 2021.
  • Serial cardiovascular evaluations including echocardiography during hospitalization and follow-up visits up to 24 weeks.

Main Results:

  • 25 out of 38 children had cardiovascular involvement, with left ventricular dysfunction and coronary abnormalities noted in 11 cases each on admission.
  • Cardiovascular involvement was more prevalent in males and children over 10 years old.
  • While mortality was 2.6%, most patients showed rapid recovery, though 5 cases had persistent coronary abnormalities.

Conclusions:

  • Cardiovascular abnormalities associated with MIS-C in children generally resolve rapidly within the first month.
  • Long-term follow-up, particularly for coronary artery health, is advised for pediatric MIS-C patients.
Abstract

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