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Self-management interventions for people with multiple sclerosis: A systematic review and meta-analysis protocol
Reza Heidari-Soureshjani1, Alireza Nikbakht Nasrabadi1, Masoumeh Zakerimoghadam1
1School of Nursing and Midwifery Tehran University of Medical Sciences Tehran Iran.
This study systematically reviews self-management interventions (SMI) for multiple sclerosis (MS) to determine their effectiveness in improving patient outcomes. Findings will guide the development of targeted MS self-management programs.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Health Services Research
Background:
- Self-management interventions (SMI) are crucial for managing multiple sclerosis (MS) symptoms, preventing relapse, and enhancing quality of life (QoL).
- There is limited understanding of the overall effectiveness of MS self-management programs and which specific interventions yield the best results.
- This research addresses the knowledge gap regarding the efficacy of structured SMI in improving health outcomes for people with MS (PwMS).
Purpose of the Study:
- To systematically assess the efficacy of structured self-management interventions in improving health outcomes for people with multiple sclerosis.
- To compare the effectiveness of different types of self-management interventions on key health outcomes in MS patients.
- To identify the most effective components of self-management interventions for targeted application in specific MS subpopulations.
Main Methods:
- A systematic review protocol will be employed, searching major databases (PubMed, Web of Science, Scopus, EMBASE, CENTRAL) and gray literature.
- Keywords related to self-management and MS will be used for articles published from 2000 to July 2023.
- Data extraction and risk of bias assessment using Cochrane's tool will be performed by two independent researchers, with potential meta-analysis using random effect models in STATA.
Main Results:
- The comparative effectiveness of various self-management interventions (SMI) for MS is currently unknown.
- The review will analyze outcome measures including quality of life (QoL), depression, self-efficacy, pain, and fatigue.
- Identification of the most promising components of SMIs will be a key outcome.
Conclusions:
- The findings will elucidate the comparative effectiveness of different self-management strategies for multiple sclerosis.
- This research will inform the design of more effective, targeted self-management interventions for people with MS.
- Optimized interventions can lead to improved symptom management, reduced relapse rates, and enhanced quality of life for individuals with MS.
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