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Updated: Jul 17, 2025
Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
Published on: March 1, 2013
A high-throughput approach of screening nanoparticles for targeted delivery of mRNA
Jennifer Khirallah1, Qiaobing Xu1
1Department of Biomedical Engineering, Tufts University, Medford, MA 02155, USA.
Abstract:
The ability to specifically and efficiently deliver mRNA to target locations could unlock therapeutic strategies for a range of diseases. Rhym et al.1 have developed an advanced approach for high-throughput, in vivo screening of tissue-targeting nanoparticle formulations, utilizing peptide barcoding and liquid chromatography with tandem mass spectrometry.
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