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Laser-induced forward transfer based laser bioprinting in biomedical applications
Jinlong Chang1, Xuming Sun1,2
1School of Medical Engineering, Xinxiang Medical University, Xinxiang, China.
Frontiers in Bioengineering and Biotechnology
|September 6, 2023
Summary
Laser-induced forward transfer (LIFT) bioprinting precisely fabricates complex biological structures. This review explores LIFT applications in tissue engineering and biomolecular microarrays, highlighting its potential and challenges.
Area of Science:
- Biomedical Engineering
- Biotechnology
- Regenerative Medicine
Background:
- Bioprinting leverages 3D printing for biological structure fabrication.
- Laser-induced forward transfer (LIFT) offers high precision and cell viability.
- LIFT is crucial for developing biomolecular microarrays and tissue engineering scaffolds.
Purpose of the Study:
- To review the principles and applications of LIFT bioprinting.
- To summarize advancements in LIFT for tissue and biomaterial fabrication.
- To identify challenges and suggest future research directions in LIFT bioprinting.
Main Methods:
- Review of experimental setups and bioink ejection mechanisms in LIFT.
- Analysis of parameters influencing LIFT bioprinting precision and cell viability.
- Compilation of current and emerging applications of LIFT technology.
Main Results:
- LIFT enables precise fabrication of complex 3D biological architectures.
- Successful applications include biomolecular microarrays, skin, blood vessels, and bone tissue constructs.
- High printing resolution and cell viability are key advantages of LIFT.
Conclusions:
- LIFT bioprinting is a powerful tool for tissue engineering and biomedical applications.
- Addressing current challenges will further enhance LIFT's capabilities.
- Continued research is vital for advancing LIFT-based biomedical innovations.
