Patent profile for the approved and in clinical trials Mpox vaccines
Irene von der Weid1, Cristina d'Urso de Souza Mendes1, Paula C Fonseca2
1National Institute of Industrial Property, Division of Studies & Projects, Rio de Janeiro, Rio de Janeiro, 20090-910, Brazil.
Abstract:
Mpox disease was reported in 110 countries since May 2022, with 88,026 cases and 148 deaths by 21 June 2023. Although some drugs were already approved for Mpox treatment, the available smallpox vaccines can provide 85% cross-prevention, but there are no scientific publications describing the patent portfolio for Mpox vaccines. This paper aims to contribute to the identification of the status of the smallpox vaccine patents now applied for Mpox. We retrieved ten vaccines, but only a few had a patent portfolio and one under patent litigation processes in three continents. Also, no specific Mpox vaccine was retrieved and, in this sense, technological monitoring studies should be performed to provide a future vision regarding Mpox prophylaxis.
Insights
This study analyzed smallpox vaccine patents for mpox (monkeypox) prevention. Few patents exist, with one in litigation, highlighting a need for mpox-specific vaccine development and patent monitoring.
Area of Science:
- Virology
- Immunology
- Intellectual Property Law
Background:
- Mpox (monkeypox) has spread globally since May 2022, causing significant public health concern.
- Existing smallpox vaccines offer cross-protection against mpox, but specific mpox vaccines are lacking.
- No comprehensive analysis of the patent landscape for mpox vaccines has been published.
Purpose of the Study:
- To identify the patent status of smallpox vaccines currently applied for mpox (monkeypox) prevention.
- To analyze the existing patent portfolios and potential legal challenges for these vaccines.
- To provide insights into the intellectual property landscape for mpox prophylaxis.
Main Methods:
- Systematic search for patents related to smallpox vaccines with potential mpox application.
- Analysis of retrieved patents, including patent holder, geographical coverage, and litigation status.
- Review of scientific literature for publications on mpox vaccine development and intellectual property.
Main Results:
- Ten smallpox vaccines with potential mpox application were identified.
- Only a limited number of these vaccines possess established patent portfolios.
- One vaccine is currently involved in patent litigation proceedings across three continents.
- No patents for vaccines specifically developed for mpox were found.
Conclusions:
- The current patent landscape for mpox vaccines is underdeveloped, with limited intellectual property protection.
- The ongoing patent litigation highlights complexities in vaccine intellectual property.
- Further technological monitoring and research are crucial for developing specific mpox vaccines and securing future prophylaxis.
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