Patent profile for the approved and in clinical trials Mpox vaccines

Irene von der Weid1, Cristina d'Urso de Souza Mendes1, Paula C Fonseca2

  • 1National Institute of Industrial Property, Division of Studies & Projects, Rio de Janeiro, Rio de Janeiro, 20090-910, Brazil.

PubMed

Insights

This study analyzed smallpox vaccine patents for mpox (monkeypox) prevention. Few patents exist, with one in litigation, highlighting a need for mpox-specific vaccine development and patent monitoring.

Area of Science:

  • Virology
  • Immunology
  • Intellectual Property Law

Background:

  • Mpox (monkeypox) has spread globally since May 2022, causing significant public health concern.
  • Existing smallpox vaccines offer cross-protection against mpox, but specific mpox vaccines are lacking.
  • No comprehensive analysis of the patent landscape for mpox vaccines has been published.

Purpose of the Study:

  • To identify the patent status of smallpox vaccines currently applied for mpox (monkeypox) prevention.
  • To analyze the existing patent portfolios and potential legal challenges for these vaccines.
  • To provide insights into the intellectual property landscape for mpox prophylaxis.

Main Methods:

  • Systematic search for patents related to smallpox vaccines with potential mpox application.
  • Analysis of retrieved patents, including patent holder, geographical coverage, and litigation status.
  • Review of scientific literature for publications on mpox vaccine development and intellectual property.

Main Results:

  • Ten smallpox vaccines with potential mpox application were identified.
  • Only a limited number of these vaccines possess established patent portfolios.
  • One vaccine is currently involved in patent litigation proceedings across three continents.
  • No patents for vaccines specifically developed for mpox were found.

Conclusions:

  • The current patent landscape for mpox vaccines is underdeveloped, with limited intellectual property protection.
  • The ongoing patent litigation highlights complexities in vaccine intellectual property.
  • Further technological monitoring and research are crucial for developing specific mpox vaccines and securing future prophylaxis.

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