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A case of primary mesenteric synovial sarcoma: a challenging presentation
Nihed Abdessayed1,2, Malek Barka3, Samiha Mabrouk1
1Department of Pathology, Farhat Hached University Hospital, Sousse, Tunisia.
Surgical Case Reports
|September 6, 2023
Summary
A rare intra-abdominal synovial sarcoma (SS) mimicked ovarian cancer. This case highlights the importance of considering soft tissue sarcomas in abdominal pain diagnoses, even when symptoms suggest other origins.
Area of Science:
- Oncology
- Pathology
- Surgical Oncology
Background:
- Synovial sarcoma is a rare soft tissue malignancy.
- Intra-abdominal presentation is exceedingly uncommon with non-specific signs.
Purpose of the Study:
- To report a case of mesenteric monophasic synovial sarcoma.
- To discuss its mimicry of ovarian malignancy.
- To emphasize clinicopathological features and differential diagnoses.
Main Methods:
- Case report of a young female with acute abdominopelvic pain.
- Diagnostic imaging (ultrasound, CT) and coelioscopy with biopsies.
- Histopathological and immunohistochemical analysis.
- Surgical management and chemotherapy.
Main Results:
- Initial diagnosis suggested ovarian origin or GIST.
- Pathology confirmed mesenteric monophasic synovial sarcoma invading appendicular wall.
- Positive surgical margins were noted.
- Patient responded well to chemotherapy and remains disease-free at 9 months.
Conclusions:
- Mesenteric monophasic synovial sarcoma can mimic ovarian malignancy.
- Accurate diagnosis requires thorough clinicopathological evaluation.
- Differential diagnosis is crucial for appropriate management.
