Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

2.5K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.5K
Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

310
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
310
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

2.8K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
2.8K
Diabetes: Symptoms, Diagnosis, and Complications01:15

Diabetes: Symptoms, Diagnosis, and Complications

588
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
588
Carbohydrate Metabolism01:36

Carbohydrate Metabolism

11.2K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.2K
Pathophysiology of Diabetes01:20

Pathophysiology of Diabetes

986
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
986

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[The collector's dermatitis: A case of Pyemotes spp. associated with exposure to antique wood].

Semergen·2024
Same author

[Biliary colic. Is it all?]

Semergen·2024
Same author

[Antihypertensive prescription in type 2 diabetes patients in Andalusia and SEH-LELHA 2022 guidelines: An economic cost evaluation].

Hipertension y riesgo vascular·2024
Same author

[Diabetes and women, why are we different?]

Semergen·2023
Same author

[Type 2 diabetes in Andalusia: Resources use and economic cost].

Semergen·2023
Same author

[Adherence to healthy lifestyle behaviours in patients with type 2 diabetes in Spain].

Semergen·2020
Same journal

[Adult ADHD: Underdiagnosis, healthcare barriers, and the role of primary care].

Semergen·2026
Same journal

Mepifilina in Spain: Accessible evidence, guideline positioning, utilization and proportionate reassessment.

Semergen·2026
Same journal

Trends and disparities in influenza and pneumonia associated sepsis mortality among older adults in the United States, 1999-2022: A retrospective population-based study.

Semergen·2026
Same journal

[High-impact ultrashort simulation-based pulmonary ultrasound training for Family Medicine residents: A prospective educational innovation study].

Semergen·2026
Same journal

[Biopsychosocial intervention for chronic non-cancer pain in Primary Care].

Semergen·2026
Same journal

[Underestimation of Glomerular Filtration Rate Obtained with Serum Creatinine-Based Formulas Compared to Those Using Serum Cystatin in Patients with Increased Muscle Mass].

Semergen·2026
See all related articles

Related Experiment Video

Updated: Jul 17, 2025

Isolation of Human Islets from Partially Pancreatectomized Patients
11:10

Isolation of Human Islets from Partially Pancreatectomized Patients

Published on: July 30, 2011

16.3K

[Type 3 c diabetes: Approach from the first level doctor].

M Seguí Díaz1, M P Pérez Unanua2, I Peral Martínez3

  • 1Unidad Básica de Salud de Es Castell, Menorca, España.

Semergen
|September 6, 2023
PubMed
Summary
This summary is machine-generated.

Diabetes of the exocrine pancreas (DM3c) is often misdiagnosed as type 2 diabetes. Early suspicion and diagnosis are crucial for appropriate management and to prevent complications.

Keywords:
DiabetesDiabetes tipo 3cType 3c diabetes

More Related Videos

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

2.8K
A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination
12:33

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination

Published on: June 25, 2014

65.3K

Related Experiment Videos

Last Updated: Jul 17, 2025

Isolation of Human Islets from Partially Pancreatectomized Patients
11:10

Isolation of Human Islets from Partially Pancreatectomized Patients

Published on: July 30, 2011

16.3K
A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
06:46

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

2.8K
A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination
12:33

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination

Published on: June 25, 2014

65.3K

Area of Science:

  • Endocrinology
  • Gastroenterology
  • Oncology

Context:

  • Diabetes of the exocrine pancreas (DM3c) is frequently misdiagnosed as type 2 diabetes (DM2) in 90% of cases.
  • It should be suspected in patients with a history of pancreatitis (chronic or acute) or new-onset diabetes over 50 without other causes.
  • Negative autoimmunity tests and GAD antibodies help differentiate it from other diabetes types.

Purpose:

  • To highlight the importance of suspecting and diagnosing DM3c.
  • To outline diagnostic tools for DM3c, including imaging and biomarkers.
  • To emphasize specific management considerations for DM3c.

Summary:

  • Diagnostic methods include abdominal ultrasound, CA 19.9 antigen levels, MRI, and CT scans.
  • Treatment follows DM2 guidelines but requires careful hypoglycemia monitoring due to its "fragile diabetes" nature.
  • Specific treatment for exocrine pancreatic function is necessary to prevent metabolic, malabsorptive, and nutritional issues.

Impact:

  • Improved diagnostic accuracy for DM3c, reducing misdiagnosis as DM2.
  • Enhanced patient management through tailored treatment strategies and monitoring.
  • Prevention of serious metabolic and nutritional complications associated with exocrine pancreatic dysfunction.