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A Large Animal Model for Acute Kidney Injury by Temporary Bilateral Renal Artery Occlusion
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Published on: February 2, 2021

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Acute Kidney Injury Management Strategies Peri-Cardiovascular Interventions

Sanjay Chaudhary1, Kianoush B Kashani2

  • 1Department of Critical Care Medicine, Mayo Clinic, 4500 San Pablo Road South, Jacksonville, FL 32224, USA.

Interventional Cardiology Clinics
|September 6, 2023
PubMed

Insights

Acute kidney injury (AKI) is a common cardiac intervention complication. This review covers AKI causes, prevention, and management to improve patient outcomes and reduce healthcare costs.

Area of Science:

  • Cardiology
  • Nephrology
  • Critical Care Medicine

Background:

  • Aging populations and comorbidities increase cardiac intervention demand.
  • Acute kidney injury (AKI) is a frequent complication of cardiac interventions.
  • AKI elevates mortality, leads to chronic kidney disease, and increases healthcare costs.

Purpose of the Study:

  • To review current knowledge on AKI pathophysiology in the peri-interventional period.
  • To discuss risk factors, preventive strategies, and management of AKI.
  • To provide an up-to-date overview for clinicians and researchers.

Main Methods:

  • Literature review of recent studies on peri-interventional AKI.
  • Synthesis of information on AKI pathophysiology (contrast-associated AKI, hemodynamic changes, cardiorenal syndrome, atheroembolism).
  • Analysis of preventive measures and management strategies.

Main Results:

  • AKI pathophysiology involves multiple complex mechanisms.
  • Effective prevention strategies include dose limitation of contrast media, hemodynamic optimization, and avoidance of nephrotoxins.
  • Management requires a multidisciplinary approach.

Conclusions:

  • AKI poses significant risks following cardiac interventions.
  • Proactive preventive measures are crucial for mitigating AKI incidence and severity.
  • Optimizing peri-interventional care can improve patient prognosis and reduce economic burden.

Keywords:
Acute kidney injuryAtheroembolismCardiac interventionCardiorenal syndromeContrast media

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