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Related Concept Videos

Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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Factors Affecting Renal Clearance: Renal Impairment01:17

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Renal dysfunction significantly impairs the renal clearance of drugs, leading to potential complications in drug therapy. Renal failure, which can be caused by various factors, poses a significant challenge in the elimination of drugs from the body.
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
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Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Cardiac Catheterization I: Pre-Procedure Overview01:28

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Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
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Urinary Tract Calculi VI: Surgical Management01:25

Urinary Tract Calculi VI: Surgical Management

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Procedures for Kidney StonesMedical intervention is necessary when kidney stones or renal calculi are too large to pass spontaneously (typically greater than 5 millimeters) when stones are accompanied by symptomatic infection (such as fever or pyelonephritis), when they impair kidney function, or when they cause persistent symptoms like severe pain, nausea, or urinary retention. Additionally, patients with only one kidney or those who cannot be treated with medical management also require...
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Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

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Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
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Updated: Jul 17, 2025

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
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Renalism: Avoiding Procedure, More Harm than Good?

Radha K Adusumilli1, Steven Coca2

  • 1UTHSCSA, San Antonio, TX, USA.

Interventional Cardiology Clinics
|September 6, 2023
PubMed
Summary
This summary is machine-generated.

Managing chronic kidney disease (CKD) is challenging due to its complex pathophysiology. Physicians fear worsening kidney function, hindering interventions that could improve outcomes for CKD patients, who face high cardiovascular disease risks.

Keywords:
Acute kidney injuryChronic kidney diseaseContrast-associated nephropathyRenalism

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Area of Science:

  • Nephrology
  • Cardiology
  • Internal Medicine

Background:

  • Chronic kidney disease (CKD) management presents significant pathophysiological complexities.
  • Cardiovascular disease (CVD) is a primary cause of mortality in CKD patients.
  • CKD patients are susceptible to acute kidney injury (AKI) and creatinine elevation.

Purpose of the Study:

  • To address the challenges in managing CKD patients.
  • To explore the impact of physician hesitancy on patient outcomes.
  • To identify barriers to providing essential interventions for CKD.

Main Methods:

  • Literature review on CKD pathophysiology and treatment.
  • Analysis of clinical guidelines and physician practices.
  • Case study review of interventions in CKD patients.

Main Results:

  • Physicians' fear of precipitating acute kidney injury (AKI) or worsening CKD (renalism) is a major barrier.
  • This fear prevents the delivery of interventions proven to reduce morbidity and mortality.
  • CKD patients face suboptimal care due to these management complexities.

Conclusions:

  • Overcoming the fear of renalism is crucial for effective CKD management.
  • Clinically indicated interventions should be prioritized despite potential risks.
  • Improved strategies are needed to enhance patient outcomes in chronic kidney disease.