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Related Concept Videos

Electrocardiogram01:29

Electrocardiogram

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An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
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Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
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Related Experiment Video

Updated: Jul 17, 2025

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
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Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

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Noninvasive Electrical Mapping Compared with the Paced QRS Complex for Optimizing CRT Programmed Settings and

Frances L Morales1, Derek J Bivona1, Mohamad Abdi1

  • 1University of Virginia Health System, Charlottesville, VA, 22901, USA.

Journal of Cardiovascular Translational Research
|September 6, 2023
PubMed
Summary
This summary is machine-generated.

Body surface electrical mapping accurately predicts cardiac resynchronization therapy (CRT) success. This 3-D mapping approach identifies optimal pacing strategies, leading to improved heart function and outcomes in patients receiving CRT.

Keywords:
Cardiac magnetic resonanceCardiac resynchronization therapyElectrical mappingHeart failureRight ventricular function

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Area of Science:

  • Cardiology
  • Medical Imaging
  • Electrophysiology

Background:

  • Cardiac resynchronization therapy (CRT) is a key treatment for heart failure.
  • Optimizing CRT pacing strategies remains a challenge.
  • Predicting patient response to CRT is crucial for improving outcomes.

Purpose of the Study:

  • To evaluate if body surface electrical mapping can identify optimal CRT pacing strategies.
  • To determine if electrical mapping predicts CRT outcomes.
  • To assess the correlation between electrical activation times and cardiac function.

Main Methods:

  • Utilized a 252-electrode vest (CardioInsight) for body surface electrical mapping in 30 patients.
  • Defined left ventricular (LV), right ventricular (RV), and biventricular (BIV) electrical activation times (LV80, RV80, BIV80).
  • Correlated electrical mapping parameters with post-CRT cardiac function, myocardial oxygen uptake, and B-type natriuretic peptide (BNP) levels.

Main Results:

  • Smaller differences in LV80 and RV80 (|LV80-RV80|) with synchronized LV pacing predicted better post-CRT LV function.
  • A lower RV80 correlated with better pre-CRT RV ejection fraction and predicted improved myocardial oxygen uptake post-CRT.
  • A lower LV80 with BIV pacing predicted lower post-CRT BNP levels, indicating improved heart function.

Conclusions:

  • 3-D electrical mapping effectively predicts favorable post-CRT outcomes.
  • Electrical mapping provides valuable insights for tailoring effective CRT pacing strategies.
  • This non-invasive mapping technique offers a promising approach to optimize CRT therapy.