Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Electrocardiogram01:29

Electrocardiogram

2.4K
An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and...
2.4K
Pulse rhythm01:30

Pulse rhythm

832
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
832

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Modeling Approach to Inform In Vitro Hypoxia Platforms for Patient-Specific Analyses.

Annals of biomedical engineering·2026
Same author

Semaglutide Reverses Ectopic Lipid Accumulation, Impaired Myocardial Perfusion Reserve, and Diastolic Dysfunction in a Mouse Model of Cardiometabolic Heart Disease.

JACC. Basic to translational science·2026
Same author

Optimal pace timing for left bundle branch area pacing with or without an additional LV lead: results from the CSPOT study.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology·2026
Same author

Screening Smarter: A Quantitative Approach to Reduce Inappropriate Shocks From Subcutaneous ICDs.

Circulation. Arrhythmia and electrophysiology·2026
Same author

2026 HRS/AHA/APHRS/EHRA/IDSA/LAHRS/PACES/STS expert consensus statement update on cardiovascular implantable electronic device lead management and extraction.

Heart rhythm·2026
Same author

Cardiac Magnetic Resonance to Define Myocardial Structure in Obesity-Associated Heart Failure.

Current cardiology reports·2026

Related Experiment Video

Updated: Jul 17, 2025

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

684

Noninvasive Electrical Mapping Compared with the Paced QRS Complex for Optimizing CRT Programmed Settings and

Frances L Morales1, Derek J Bivona1, Mohamad Abdi1

  • 1University of Virginia Health System, Charlottesville, VA, 22901, USA.

Journal of Cardiovascular Translational Research
|September 6, 2023
PubMed
Summary
This summary is machine-generated.

Body surface electrical mapping accurately predicts cardiac resynchronization therapy (CRT) success. This 3-D mapping approach identifies optimal pacing strategies, leading to improved heart function and outcomes in patients receiving CRT.

Keywords:
Cardiac magnetic resonanceCardiac resynchronization therapyElectrical mappingHeart failureRight ventricular function

More Related Videos

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

14.8K
Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
09:36

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia

Published on: December 22, 2023

1.2K

Related Experiment Videos

Last Updated: Jul 17, 2025

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
10:17

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System

Published on: April 11, 2025

684
Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

14.8K
Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
09:36

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia

Published on: December 22, 2023

1.2K

Area of Science:

  • Cardiology
  • Medical Imaging
  • Electrophysiology

Background:

  • Cardiac resynchronization therapy (CRT) is a key treatment for heart failure.
  • Optimizing CRT pacing strategies remains a challenge.
  • Predicting patient response to CRT is crucial for improving outcomes.

Purpose of the Study:

  • To evaluate if body surface electrical mapping can identify optimal CRT pacing strategies.
  • To determine if electrical mapping predicts CRT outcomes.
  • To assess the correlation between electrical activation times and cardiac function.

Main Methods:

  • Utilized a 252-electrode vest (CardioInsight) for body surface electrical mapping in 30 patients.
  • Defined left ventricular (LV), right ventricular (RV), and biventricular (BIV) electrical activation times (LV80, RV80, BIV80).
  • Correlated electrical mapping parameters with post-CRT cardiac function, myocardial oxygen uptake, and B-type natriuretic peptide (BNP) levels.

Main Results:

  • Smaller differences in LV80 and RV80 (|LV80-RV80|) with synchronized LV pacing predicted better post-CRT LV function.
  • A lower RV80 correlated with better pre-CRT RV ejection fraction and predicted improved myocardial oxygen uptake post-CRT.
  • A lower LV80 with BIV pacing predicted lower post-CRT BNP levels, indicating improved heart function.

Conclusions:

  • 3-D electrical mapping effectively predicts favorable post-CRT outcomes.
  • Electrical mapping provides valuable insights for tailoring effective CRT pacing strategies.
  • This non-invasive mapping technique offers a promising approach to optimize CRT therapy.