Guidelines for high-flow nasal cannula oxygen therapy in neonates (2022)

Area of Science:

• Neonatal Medicine
• Respiratory Therapy
• Evidence-Based Practice

Background:

• High-flow nasal cannula (HFNC) therapy is a key noninvasive respiratory support method.
• Its use is expanding in critically ill neonates due to comfort, ease of use, and low nasal trauma.
• Recent research has focused on HFNC advantages, indications, and risks.

Purpose of the Study:

• To develop evidence-based guidelines for HFNC use in neonates.
• To standardize and optimize HFNC oxygen therapy in clinical practice.
• To ensure more neonates benefit from this respiratory support modality.

Main Methods:

• Guidelines developed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework.
• Extensive consultations held with neonatologists, respiratory therapists, nurse specialists, and evidence-based medicine experts.
• Formulated 24 recommendations addressing 9 key questions regarding HFNC in neonates.

Main Results:

• A comprehensive set of 24 recommendations for HFNC in neonates has been established.
• Guidelines are based on current evidence and expert consensus.
• The recommendations cover critical aspects of HFNC application in neonatal respiratory failure.

Conclusions:

• The developed guidelines serve as a vital evidence source and reference for HFNC oxygen therapy.
• Implementation of these guidelines aims to enhance respiratory support for neonates.
• These recommendations are expected to improve outcomes for neonates and their families.