Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A thousand operations for ulcer disease.

C E Welch, G V Rodkey, P von Ryll Gryska

    Annals of Surgery
    |October 1, 1986
    PubMed
    Summary
    This summary is machine-generated.

    Surgical operations for peptic ulcer disease decreased significantly from 1974-1986, with fewer elective procedures but stable rates for emergency surgeries. Mortality rates varied by operation type, with organ failure and sepsis being leading causes of death.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Acute and chronic cholecystitis.

    The New England journal of medicine·2010
    Same author

    Subtotal gastrectomy for duodenal ulcer.

    Annals of surgery·2010
    Same author

    Embolism, superior mesenteric artery; arteriosclerosis, generalized, severe.

    The New England journal of medicine·2010
    Same author

    Carcinoma of sigmoid, with ileocolic fistula; clinicopathological exercises.

    The New England journal of medicine·2010
    Same author

    War wounds of the abdomen.

    The New England journal of medicine·2010
    Same author

    War wounds of the abdomen.

    The New England journal of medicine·2010
    Same journal

    Real-world Safety and Performance of the Symani Surgical System® in Microsurgical Reconstructive Procedures: Primary Results from the PRIMO Study.

    Annals of surgery·2026
    Same journal

    Revisiting Simultaneous Liver and Kidney Transplantation from Donors After Circulatory Death in the Era of Machine Perfusion Technologies: A US Nationwide Analysis of 10,687 Cases.

    Annals of surgery·2026
    Same journal

    The International Medical Graduate Paradox.

    Annals of surgery·2026
    Same journal

    Defining the Incremental Value of Endoscopic Ultrasound in Assessing Pancreatic Cystic Neoplasms.

    Annals of surgery·2026
    Same journal

    Trends in Metabolic and Bariatric Surgery and GLP-1 Receptor Agonist Use Among Adolescents with Severe Obesity.

    Annals of surgery·2026
    Same journal

    The Ambulatory Surgery Center Paradox: Why 60% of Surgeries Occur Where 2% of AI Research Happens.

    Annals of surgery·2026
    See all related articles

    Area of Science:

    • Gastroenterology
    • Surgical Oncology
    • Clinical Epidemiology

    Background:

    • Peptic ulcer disease historically required surgical intervention.
    • The advent of cimetidine marked a potential shift in treatment paradigms.
    • Understanding surgical trends and outcomes is crucial for patient care.

    Purpose of the Study:

    • To analyze trends in peptic ulcer disease operations over a 12-year period.
    • To evaluate mortality rates associated with different surgical procedures.
    • To identify early and late complications following peptic ulcer surgery.

    Main Methods:

    • Retrospective study of 1068 patients undergoing peptic ulcer surgery.
    • Data collected from January 1, 1974, to January 1, 1986, at Massachusetts General Hospital.

    Related Experiment Videos

  • Analysis of admission rates, operation types, mortality, and complication rates.

    • Main Results:

    • A 39.3% decline in peptic ulcer disease admissions and a 16.5% decrease in annual operations were observed.
    • Elective duodenal ulcer operations showed the greatest decline; emergency operations for hemorrhage and perforation remained constant.
    • Overall mortality was 10.3%, with significant variation based on surgical urgency and indication.

    Conclusions:

    • Surgical interventions for peptic ulcer disease decreased, likely influenced by medical advancements.
    • Mortality risk is substantially higher for emergency and urgent procedures compared to elective ones.
    • Key complications include organ failure, sepsis, early postoperative hemorrhage, and late recurrence, necessitating careful patient management.