Nanofibers: A current era in drug delivery system

Area of Science:

• Biomaterials Science
• Nanotechnology
• Materials Engineering

Background:

• Nanofibers possess unique properties like large surface area, 3D topography, and porosity.
• These characteristics make them suitable for addressing challenges in diverse fields, including medicine.

Purpose of the Study:

• To systematically review the history, advantages, disadvantages, and types of nanofibers.
• To summarize polymers and fabrication methods, focusing on electrospinning.
• To discuss current applications and recent advancements in nanofabrication technology.

Main Methods:

• Literature review of nanofiber technology.
• Systematic study of fabrication techniques (electrospinning, phase separation, etc.).
• Analysis of various polymer types used in nanofiber preparation.

Main Results:

• Nanofibers are fabricated using diverse techniques and a wide range of materials (polymers, metals, ceramics).
• Nanofiber composites show promise for targeted delivery of genes, proteins, peptides, and growth factors.
• Electrospinning is a primary fabrication method with various specialized types.

Conclusions:

• Nanofibers hold significant potential for revolutionizing drug delivery and various therapeutic applications.
• Continued research in nanofabrication is crucial for advancing medical treatments.
• The versatility of nanofibers makes them a key area for future scientific exploration.