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PCRRT-ICONIC critical care pediatric nephrology course: the global prevalence of COVID-19 and associated sequelae

Rupesh Raina1,2, Nina Vijayvargiya1,2, Riti Kalra1,2

  • 1Akron Nephrology Associates, Department of Nephrology, Cleveland Clinic Akron General Medical Center, Akron, OH, United States.

Frontiers in Nephrology
|September 7, 2023
PubMed

Insights

COVID-19 impacts children's kidneys, causing acute kidney injury (AKI) and chronic kidney disease (CKD). This review synthesizes global data on pediatric kidney complications from COVID-19.

Area of Science:

  • Nephrology
  • Pediatrics
  • Infectious Diseases

Background:

  • COVID-19 (Coronavirus Disease 2019) extends beyond respiratory effects, significantly impacting pediatric kidney health.
  • Acute kidney injury (AKI) and chronic kidney disease (CKD) are recognized complications in children affected by COVID-19.
  • Vulnerable pediatric groups include transplant recipients, those with multisystem inflammatory syndrome (MIS-C), and patients on dialysis.

Purpose of the Study:

  • To analyze the detrimental effects of COVID-19 on pediatric kidney disease.
  • To integrate international data on managing renal complications in children with COVID-19.
  • To enhance scientific understanding of global pediatric COVID-19 renal outcomes.

Main Methods:

  • Review of severe COVID-19 cases in the global pediatric population.
  • Integration of international perspectives, statistics, and treatment strategies.
  • Focus on critical care nephrology and dialysis management.

Main Results:

  • Significant breakthroughs in understanding AKI and CKD development in pediatric COVID-19 cases.
  • Identification of specific pediatric patient groups at higher risk for renal complications.
  • Compilation of global data on the incidence and severity of kidney issues.

Conclusions:

  • COVID-19 poses substantial risks to pediatric kidney health, necessitating further research.
  • International collaboration is crucial for developing effective management strategies for renal complications.
  • Continued investigation is vital to address knowledge gaps in pediatric COVID-19 nephrology.

Keywords:
COVID-19acute kidney injurychronic kidney diseasemultisystem inflammatory syndromenephrologypediatrics

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