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Updated: Jul 17, 2025

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Rapid Remission of Sunburn-Induced Guttate Psoriasis with Guselkumab
Erin Bartholomew1, Bo-Young Chung1,2, Mitchell Davis1
1Department of Dermatology, The University of California, San Francisco (UCSF), 2340 Sutter Street, Box 0808, San Francisco, CA, 94115, USA.
Abstract:
Guselkumab is an anti-interleukin-23 monoclonal antibody that is approved for plaque psoriasis and psoriatic arthritis. We present a case of a 28-year-old female patient with acute onset of guttate psoriasis after a blistering sunburn. She had no personal or family history of psoriasis or chronic inflammatory skin disease. The guttate psoriasis was refractory to topical treatment. After the first dose of guselkumab (100 mg subcutaneous injection), the patient experienced near-clearance of her guttate psoriasis, with continued improvement and drug-free remission 8 months after cessation of treatment. Dermatologists could consider guselkumab as a treatment option for patients with guttate psoriasis. Future studies should examine the potential for guselkumab to induce drug-free remissions in guttate psoriasis.
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