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Bioinspired Soft Robot with Incorporated Microelectrodes
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Soft Bioelectronics for Therapeutics.

Zongman Zhang1,2, Zhongtai Zhu1, Pengcheng Zhou1,2

  • 1Department of Chemical Engineering, Guangdong Technion-Israel Institute of Technology, 241 Daxue Road, Shantou, Guangdong 515063, China.

ACS Nano
|September 7, 2023
PubMed
Summary
This summary is machine-generated.

Advanced soft bioelectronics offer precise, patient-friendly therapeutic solutions for diverse conditions. This review explores current applications and future potential for personalized medicine.

Keywords:
closed-loop systemsdrug delivery systemsfeedback stimulationhigh-precision therapeuticsimplantable therapeuticspersonalized healthcaresoft bioelectronicswearable therapeutics

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Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Medical Devices

Background:

  • Soft bioelectronics are essential for advanced therapeutics, offering advantages like biocompatibility and patient comfort.
  • Their unique properties enable high-precision treatments for various medical conditions.

Purpose of the Study:

  • To provide a comprehensive review of current therapeutic applications of soft bioelectronics.
  • To highlight challenges and opportunities for clinical translation and commercialization.

Main Methods:

  • Literature review of recent advancements in soft bioelectronic therapeutics.
  • Categorization of applications into wearable and implantable devices.
  • Analysis of clinical translation and commercialization barriers.

Main Results:

  • Soft bioelectronics are utilized in wearable devices for skin wounds, diabetes, and ophthalmic/muscle disorders.
  • Implantable soft bioelectronics show promise for cardiac arrhythmias, cancer, and neurological diseases.
  • Key challenges include manufacturing, long-term stability, and regulatory pathways.

Conclusions:

  • Soft bioelectronics represent a rapidly evolving field with significant potential for personalized medicine.
  • Overcoming current challenges is crucial for widespread clinical adoption and commercial success.