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Avelumab First-Line Maintenance Therapy: Managing Patients With Advanced Urothelial Carcinoma
Maria Lapuente1, Dawn Conway2, Laura S Wood3
1St. Bartholomew's Hospital.
Clinical Journal of Oncology Nursing
|September 7, 2023
Summary
Avelumab maintenance therapy significantly improves overall survival for patients with advanced urothelial carcinoma. Oncology nurses play a crucial role in its effective clinical implementation and patient care.
Area of Science:
- Oncology
- Immunotherapy
- Urothelial Carcinoma
Background:
- The JAVELIN Bladder 100 trial established avelumab as a first-line maintenance standard of care for advanced urothelial carcinoma.
- It offers significant overall survival benefits for platinum-eligible patients post-chemotherapy.
Approach:
- This article focuses on practical considerations for oncology nurses.
- It reviews clinical evidence and implications for implementing avelumab first-line maintenance therapy.
Key Points:
- Oncology nurses are vital for patient education and caregiver support.
- Ensuring correct administration and prompt management of immune-related adverse events are critical.
- Comprehensive care optimizes the use of avelumab in advanced urothelial carcinoma.
Conclusions:
- Avelumab first-line maintenance is a new standard of care for advanced urothelial carcinoma.
- Effective nursing implementation is key to maximizing patient outcomes and safety.
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