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Updated: Jul 17, 2025

Dual-Dye Optical Mapping of Hearts from RyR2R2474S Knock-In Mice of Catecholaminergic Polymorphic Ventricular Tachycardia
Published on: December 22, 2023
[Cardiac sarcoidosis revealed by recurrent ventricular tachycardia]
Alois Castro1, Floriane Gilles1, Sonia Marrakchi2
1Service de cardiologie, Centre Hospitalier de Versailles, Hôpital André Mignot, Le Chesnay Rocquencourt, Paris, France.
Abstract:
Sarcoidosis is an inflammatory disease whose diagnosis is suggested by clinical and paraclinical signs and confirmed by histological evidence showing granulomatosis without caseous necrosis. The clinical presentation is sometimes misleading and the diagnosis difficult to confirm. We report here the case of a young woman with cardiac sarcoidosis of difficult diagnosis, revealed by a myocardial infarction with normal coronary angiography and recurrent ventricular tachycardia. Multimodal imaging, combined with left ventricular endomyocardial biopsies guided by electrophysiological analysis and endocavitary mapping, finally confirmed the diagnosis, and allowed effective medical treatment.
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