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Turkey coryza: lack of correlation between plasmids and pathogenicity of Bordetella avium

D G Simmons, L P Rose, F J Fuller

    Avian Diseases
    |July 1, 1986
    PubMed

    Insights

    Researchers removed plasmids from pathogenic Bordetella avium using various treatments. Plasmid removal did not affect the pathogenicity of Bordetella avium in turkey poults.

    Area of Science:

    • Microbiology
    • Veterinary Science
    • Bacterial Genetics

    Background:

    • Bordetella avium is a pathogen that affects poultry.
    • Plasmids are extrachromosomal DNA elements that can carry virulence factors.

    Purpose of the Study:

    • To determine the efficacy of different treatments for plasmid removal from Bordetella avium.
    • To assess the impact of plasmid removal on the pathogenicity of Bordetella avium.

    Main Methods:

    • Bacterial cultures of Bordetella avium were subjected to various plasmid-curing treatments.
    • Plasmid-cured strains were confirmed through molecular methods.
    • Pathogenicity was evaluated in turkey poult models.

    Main Results:

    • Successful removal of plasmids was achieved with certain treatments, with varying cure rates depending on the isolate.
    • The presence or absence of plasmids did not significantly alter the pathogenicity of Bordetella avium in turkey poults.

    Conclusions:

    • Plasmid removal is feasible in Bordetella avium, though treatment efficacy varies.
    • Plasmids in the tested Bordetella avium isolates do not appear to be essential for pathogenicity in turkey poults.

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