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Population level screening for celiac disease: is now the time?
Brianne Shuler1, Edwin Liu, Marisa G Stahl
1Digestive Health Institute, Department of Pediatrics, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Current Opinion in Gastroenterology
|September 7, 2023
Summary
Celiac disease screening identifies individuals with unrecognized symptoms, improving nutrition, growth, bone health, and quality of life. Despite insufficient evidence for general screening, identified patients benefit from early gluten-free diet treatment.
Area of Science:
- Gastroenterology
- Immunology
- Public Health
Background:
- Increasing incidence and prevalence of celiac disease.
- Identification of subclinical and asymptomatic cases through screening.
- Current guidelines recommend against general population screening for asymptomatic individuals due to insufficient evidence.
Conclusions:
- Celiac disease screening benefits identified individuals, even those asymptomatic, by enabling timely gluten-free diet initiation.
- Further research is needed on the cost-effectiveness of mass screening approaches from a societal perspective.
