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Updated: Jul 17, 2025

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Pre-existing skin diseases as predictors of post-burn pruritus
Grace Obanigba1, Jayson W Jay2, Steven Wolf2
1John Sealy School of Medicine, University of Texas Medical Branch, Galveston, TX, USA.
Background:
Post-burn pruritus (PBP) has been shown to adversely affect burn patients' quality of life. However, the predictors of PBP are not known. We hypothesize a pre-existing pruritic skin diagnosis is associated with an increased risk of adverse outcomes following a burn injury.
Methods:
This retrospective study utilized data from the TriNetX electronic health record. Burn patients with a history of a pruritic skin disorder were compared to patients without a diagnosed skin disorder and the occurrence of pruritus was compared between the two cohorts.
Results:
Patients with pre-existing skin conditions were more likely to develop PBP. The risk of PBP was highest 1 year after injury. Stratification by percent TBSA burned, gender, race, and age showed an increased risk of PBP for females, Caucasians, older patients, and those with large burns.
Conclusion:
A pre-existing pruritic skin diagnosis is highly associated with developing pruritus following a burn injury.
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