Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Protection of Alcohols02:31

Protection of Alcohols

7.3K
This lesson delves into the concept of protection and deprotection of a functional group fundamental to synthetic organic chemistry. These phenomena are explained in the context of aliphatic and aromatic alcohols.
Protection
It defines a protecting group as the masking agent to make the more reactive species inert to a given set of conditions. This concept is depicted via the illustration of liquid flow through different outlets in an assembly of pipes. The analogy helps to understand the role...
7.3K
CNS Depressants: Alcohol and Nicotine01:27

CNS Depressants: Alcohol and Nicotine

241
Ethanol, a clear colorless alcohol, has been consumed by humans for millennia, but its effects on the body are far from benign. At lower doses, it induces decreased inhibitions and loquaciousness, leading to its social appeal. However, it can cause severe consequences at higher doses, such as coma and respiratory depression, due to its zero-order elimination kinetics. Chronic ethanol abuse wreaks havoc on multiple organ systems, particularly the CNS and the liver. Abrupt cessation of ethanol...
241
Alcohols from Carbonyl Compounds: Reduction02:23

Alcohols from Carbonyl Compounds: Reduction

10.5K
Reduction is a simple strategy to convert a carbonyl group to a hydroxyl group. The three major pathways to reduce carbonyls to alcohols are catalytic hydrogenation, hydride reduction, and borane reduction.
Catalytic hydrogenation is similar to the reduction of an alkene or alkyne by adding H2 across the pi bond in the presence of transition metal catalysts like Raney Ni, Pd–C, Pt, or Ru. Aldehydes and ketones can be reduced by this method, often under mild to moderate heat (25–100°C) and...
10.5K
Guidelines for Writing Outcome01:11

Guidelines for Writing Outcome

2.8K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
2.8K
Hypothesis Test for Test of Independence01:16

Hypothesis Test for Test of Independence

3.6K
The test of independence is a chi-square-based test used to determine whether two variables or factors are independent or dependent. This hypothesis test is used to examine the independence of the variables. One can construct two qualitative survey questions or experiments based on the variables in a contingency table. The goal is to see if the two variables are unrelated (independent) or related (dependent). The null and alternative hypotheses for this test are:
H0: The two variables (factors)...
3.6K
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

48
Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...
48

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Alcohol Intake and Health Study: No Protective Effect at Low Levels, With Mortality Increasing to 1 in 25 at 14 Drinks Per Week.

Journal of studies on alcohol and drugs·2026
Same author

Exploring Associations Between Substance Use, Self-Regulated Learning Practices, and Academic Challenges at Five Canadian Universities.

Journal of college student retention : research, theory & practice·2026
Same author

On the Label: Implementation of Health Warnings on Alcohol Products in 13 European Countries.

Drug and alcohol review·2026
Same author

Concurrent mental health and substance use disorders among Canadian adults during the COVID-19 pandemic: a population-based study.

Health promotion and chronic disease prevention in Canada : research, policy and practice·2026
Same author

Online promotional practices and apparent violations from licensed cannabis retail stores in Canada.

The International journal on drug policy·2026
Same author

A comparison of labelling requirements for alcohol, tobacco, and cannabis across WHO regions and implications for alcohol labelling policy in Canada.

The International journal on drug policy·2026

Related Experiment Video

Updated: Jul 17, 2025

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
08:45

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis

Published on: November 8, 2024

627

New perspectives on how to formulate alcohol drinking guidelines.

Kevin Shield1,2, Catherine Paradis3, Peter Butt4

  • 1Institute for Mental Health Policy Research, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.

Addiction (Abingdon, England)
|September 8, 2023
PubMed
Summary

New Low-Risk Alcohol Drinking Guidelines (LRDGs) should use years of life lost (YLL) as the primary metric. Presenting risk zones instead of single thresholds can better guide public health behaviors for reduced alcohol-related harm.

Keywords:
Agealcoholdeathsguidelinesharms reductionriskyears of life lost

More Related Videos

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

3.1K
A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

9.8K

Related Experiment Videos

Last Updated: Jul 17, 2025

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis
08:45

Modeling Alcohol Consumption in Rodents Using Two-Bottle Choice Home Cage Drinking and Microstructural Analysis

Published on: November 8, 2024

627
The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
05:40

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans

Published on: April 28, 2022

3.1K
A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers
08:05

A Prediction Error-driven Retrieval Procedure for Destabilizing and Rewriting Maladaptive Reward Memories in Hazardous Drinkers

Published on: January 5, 2018

9.8K

Area of Science:

  • Public Health
  • Epidemiology
  • Risk Assessment

Background:

  • Low-Risk Alcohol Drinking Guidelines (LRDGs) aim to mitigate alcohol-related harms.
  • Significant international variations exist in established 'low-risk' alcohol consumption thresholds.

Purpose of the Study:

  • To propose improvements for establishing national 'low-risk' alcohol consumption thresholds.
  • To debate the suitability of different metrics and presentation formats for LRDGs.

Main Methods:

  • Analysis of Canada's LRDGs update process.
  • Evaluation of Years of Life Lost (YLL) as a metric for health loss.
  • Consideration of age-specific, cause-specific, and composite risk function approaches.
  • Assessment of single threshold versus risk zone presentation.

Main Results:

  • Years of Life Lost (YLL) offers advantages over deaths, premature deaths, or Disability-Adjusted Life Years (DALYs) for setting guidelines.
  • Age-specific and cause-specific guidelines may be less appropriate than a whole-health approach.
  • A composite risk function considering various alcohol-related conditions is suggested.
  • Risk zones, rather than a single threshold, may be more effective for public engagement.

Conclusions:

  • National LRDGs should prioritize YLL, avoiding age- or cause-specific metrics.
  • Implementing risk zones is recommended over single drinking thresholds.
  • These changes aim to enhance public understanding and promote healthier alcohol consumption behaviors.