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Updated: Jul 17, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
Clinical Course and Optical Coherence Tomography of Ocular Angiostrongyliasis: A Case Report
Kanin Luangsawang1, Veeraphatra Wongsantimeth1, Sirinan Treeyawedkul1
1Department of Ophthalmology, Faculty of Medicine, Naresuan University, Phitsanulok, Thailand.
Purpose:
To report the clinical course and optical coherence tomography (OCT) findings of ocular angiostrongyliasis.
Methods:
A 36-year-old female with a history of ingesting regular raw freshwater shrimp and other raw food presented with acute unilateral painless visual loss in the right eye. Her right eye's best-corrected visual acuity (BCVA) was 1 ft of the count finger. Fundus examination showed vitritis, generalized retinal pigment epithelial alteration, and a moving roundworm in the vitreous at the 6 o'clock position. Macular OCT of her right eye showed thinning of the retina, loss of the external limiting membrane and ellipsoid zone, subretinal hyper-reflective material clumping, and hyper-reflective foci at the superficial choroidal layer.
Results:
The patient was administered oral and topical prednisolone. The roundworm, identified as Angiostrongylus cantonensis, was wholly extracted from the vitreous using a 23G sclerotomy port and pars plana vitrectomy. The final BCVA was 1 ft of the count finger.
Conclusion:
This case report describes an infrequent presentation and illustrates the clinical course and OCT findings of ocular angiostrongyliasis.
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