Stent retrieval for free-floating thrombus attached to carotid artery stenosis: A report of two cases
Related Experiment Video
Updated: Jul 17, 2025

A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Yuki Yamamoto1, Nobuaki Yamamoto1, Tomohiro Matsuda2
1Department of Neurology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
Insights
Mechanical thrombectomy using a stent retriever before carotid artery stenting (CAS) is feasible for carotid artery stenosis with free-floating thrombus (FFT). This approach may reduce ischemic risks, but careful consideration of indications and potential complications is crucial.
Area of Science:
- Vascular Surgery
- Interventional Neurology
- Medical Device Technology
Background:
- Carotid artery stenosis (CAS) with free-floating thrombus (FFT) poses a significant risk of stroke.
- Urgent intervention is often required for symptomatic patients with progressive neurological deficits.
Observation:
- Two cases of symptomatic CAS with FFT underwent urgent mechanical thrombectomy with a stent retriever followed by CAS.
- Successful thrombus retrieval was achieved in both cases, with varying degrees of post-procedural complications.
Findings:
- Mechanical thrombectomy using a stent retriever is technically feasible for removing FFT in CAS.
- While thrombus removal may mitigate ischemic complications, potential risks like plaque irritation and embolism exist.
Implications:
- This technique offers a potential strategy for managing complex CAS with FFT.
- Further research is needed to establish optimal indications and refine techniques to minimize procedural risks.
Background:
We report two cases who underwent mechanical thrombectomy using a stent retriever in advance of urgent carotid artery stenting (CAS) for carotid artery stenosis with free-floating thrombus (FFT).
Case Description:
Two patients showing symptomatic carotid artery stenosis with FFT underwent urgent endovascular surgery due to progressive neurological symptoms. The first case showed an FFT with 70% internal carotid artery (ICA) stenosis. After the completion of the common and external carotid artery balloon and distal ICA filter protection, we deployed a 6-mm-diameter stent retriever in the distal part of the stenosis. The white thrombus was retrieved; the angiographic shadow of the FFT disappeared; and CAS was performed. In the second case, due to a 90% severe stenosis lesion with FFT, balloon angioplasty was performed on the lesion using the push wire of the stent retriever. After angioplasty, the stent retriever was smoothly retrieved, and CAS was performed. Postoperative magnetic resonance imaging showed an increase in cerebral embolism in the first case; however, the patient's neurological symptoms improved. The second case showed in-stent plaque protrusion and required two additional stent placements; the patient showed no worsening of his neurological symptoms.
Conclusion:
In cases of carotid artery stenosis with FFT, it is technically possible to retrieve a thrombus with a stent retriever. Although thrombus removal may help reduce the risk of ischemic complications in a series of urgent CAS procedures, there are concerns such as mechanical irritation to the carotid artery plaque, and its indications and alternative treatments should be carefully considered.
More Related Videos
12:30Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers
Published on: August 12, 2014
13:10Combined Near-infrared Fluorescent Imaging and Micro-computed Tomography for Directly Visualizing Cerebral Thromboemboli
Published on: September 25, 2016