Liposarcoma of the larynx. Case report and literature review

Primary liposarcoma of the larynx is extremely rare. To our knowledge, only eight cases have been documented in the English literature. We report a ninth case in a 54-year-old man. The recurrent 2-cm tumor was well differentiated and was treated with a supraglottic laryngectomy with partial neck dissection followed by radiotherapy. There has not been a second recurrence in 16 months. The majority of liposarcomas arising in the larynx have been of a favorable histologic type (well differentiated or myxoid). The tumor tends to occur in a supraglottic location in men of 40 years or more, and multiple recurrences are typical. The primary mode of treatment is wide surgical excision, with or without postoperative radiation therapy.