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Increased blood pressure after nonsevere COVID-19

Christian Schmidt-Lauber1,2,3, Elisa Alba Schmidt1,2, Sonja Hänzelmann1,2,4

  • 1III. Department of Medicine, University Medical Center Hamburg-Eppendorf.

Journal of Hypertension
|September 8, 2023
PubMed

Insights

Nonsevere COVID-19 can lead to higher blood pressure, even months after infection. This study found increased diastolic blood pressure and hypertension rates in individuals post-COVID-19 compared to controls.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Public Health

Background:

  • Post-acute sequelae of coronavirus disease 2019 (COVID-19) are increasingly recognized.
  • Limited data exist on the long-term effects of nonsevere COVID-19 on blood pressure regulation.

Purpose of the Study:

  • To investigate blood pressure profiles in individuals following nonsevere COVID-19.
  • To compare blood pressure outcomes in individuals with and without a history of COVID-19.

Main Methods:

  • Cross-sectional analysis of blood pressure data from the Hamburg City Health Study.
  • Matching of 432 individuals post-COVID-19 with 1728 controls based on age, sex, education, and pre-existing hypertension.
  • Analysis included individuals at least 4 months post-COVID-19, with 92.8% experiencing mild or moderate illness.

Main Results:

  • Individuals post-COVID-19 exhibited significantly higher diastolic blood pressure (DBP) (+4.7 mmHg) compared to controls.
  • A trend towards increased systolic blood pressure (SBP) was observed (+1.4 mmHg).
  • Hypertensive blood pressure (≥130/80 mmHg or ≥140/90 mmHg) occurred significantly more often in the post-COVID-19 group.

Conclusions:

  • Nonsevere COVID-19 is associated with elevated blood pressure, suggesting a hypertensive sequela.
  • The findings highlight the potential for cardiovascular complications following even mild COVID-19 infections.
  • Further research is warranted to understand the mechanisms and long-term implications of post-COVID-19 hypertension.
Abstract

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