Nanotechnology-based theranostic and prophylactic approaches against SARS-CoV-2

Area of Science:

• Medical Diagnostics
• Nanotechnology
• Infectious Diseases

Background:

• The COVID-19 pandemic overwhelmed global healthcare systems, highlighting the need for improved diagnostic tools.
• Traditional methods like RT-PCR and antibody tests have limitations, including false negatives and dependence on infection stage.
• Early detection is critical for managing diseases, and nanodiagnostics offer a promising solution.

Purpose of the Study:

• To explore the role of nanotechnology in healthcare, focusing on COVID-19 management.
• To outline nanotechnology-based diagnostic devices for SARS-CoV-2 detection.
• To discuss nanomaterial applications in COVID-19 treatment and prevention.

Main Methods:

• Review of nanotechnology applications in diagnostics and healthcare.
• Focus on nanotechnology-based diagnostic devices for SARS-CoV-2.
• Discussion of nanomaterial utility in treatment, vaccines, and protective equipment.

Main Results:

• Nanodiagnostics provide specific, responsive, accurate, rapid, low-cost, and simple point-of-care tools.
• Nanomaterials enhance sensitivity and signal-to-noise ratio in diagnostic tests.
• Nanotechnology aids in developing protective equipment, vaccines, and antiviral strategies.

Conclusions:

• Nanodiagnostics are essential for early COVID-19 detection, improving upon existing methods.
• Nanotechnology offers versatile applications in COVID-19 treatment and prevention.
• Addressing challenges in accessibility is key for widespread adoption of nanodiagnostic solutions.