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Updated: Jul 17, 2025
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Fluorescent Laparoscopic Central Hepatectomy for Liver Cancer Using Indocyanine Green Negative Staining
Published on: March 17, 2023
775
[Indocyanine green in liver tumor resection]
A D Kaprin1, S A Ivanov2, L O Petrov2
1National Medical Research Radiology Center, Obninsk, Russia.
Khirurgiia
|September 8, 2023
Summary
Preoperative assessment of liver function is crucial for safe liver surgery. Indocyanine green clearance offers a precise method for evaluating liver remnant function, improving patient selection and surgical outcomes.
Area of Science:
- Hepatobiliary Surgery
- Surgical Oncology
- Diagnostic Imaging
Context:
- Primary liver cancer and colorectal cancer liver metastases are leading causes of cancer mortality.
- Surgical resection offers the best survival outcomes but requires careful preoperative planning.
- Post-resection liver failure is a significant and often fatal complication.
Purpose:
- To highlight the importance of preoperative assessment of liver functional reserves for patient selection and surgical safety.
- To discuss the utility of indocyanine green (ICG) clearance as a dynamic quantitative test for assessing liver function.
- To introduce the concept and technical aspects of fluorescent imaging in hepatobiliary surgery.
Summary:
- Accurate assessment of liver remnant function is essential to prevent post-resection liver failure.
- Traditional liver tests lack precision; dynamic quantitative tests like indocyanine green clearance are superior.
- This work details the practical application of ICG clearance and fluorescent imaging for preoperative liver evaluation.
Impact:
- Improved patient selection for liver surgery, leading to reduced complication rates.
- Enhanced surgical planning and execution in hepatobiliary procedures.
- Potential to decrease liver-related mortality by optimizing surgical strategies based on functional liver reserve.
