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National Trends in Interventions for Pediatric Gallstone Pancreatitis
Audra J Reiter1,2, Lynn Huang2, Yao Tian2
1Division of Pediatric Surgery, Department of Surgery, Northwestern University Feinberg School of Medicine, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Insights
Laparoscopic cholecystectomy (LC) rates for pediatric gallstone pancreatitis remained stable over two decades. However, interventions like LC and ERCP are happening earlier, leading to shorter hospital stays for children.
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Health Services Research
Background:
- Laparoscopic cholecystectomy (LC) is standard for adult gallstone pancreatitis during the initial hospital stay.
- Trends in managing pediatric gallstone pancreatitis, specifically the use of LC and endoscopic retrograde cholangiopancreatography (ERCP), require evaluation.
Purpose of the Study:
- To assess the trends in the utilization of LC and ERCP for pediatric patients diagnosed with gallstone pancreatitis.
- To analyze changes in the timing of these interventions and their impact on hospital length of stay (LOS).
Main Methods:
- A retrospective cohort study utilizing the Kids' Inpatient Database (2000-2019).
- Inclusion criteria: patients aged 18 or younger with a primary diagnosis of gallstone pancreatitis.
- Statistical analysis included the Mann-Kendall trend test to evaluate temporal trends.
Main Results:
- The overall rate of LC during the index hospitalization for pediatric gallstone pancreatitis remained consistent (55.4% to 63.8%).
- Interventions, including LC and ERCP, occurred earlier in the hospitalization, with average hospital days decreasing significantly for LC (4.6 to 3.4).
- Average length of stay (LOS) decreased for patients undergoing LC (6.8 to 5.1 days) and for those not undergoing procedures (5.7 to 4.0 days).
Conclusions:
- The proportion of LC performed during the index hospitalization for pediatric gallstone pancreatitis has been stable over the past 20 years.
- Interventions for pediatric gallstone pancreatitis are trending towards earlier administration within the hospital stay.
- These earlier interventions are associated with a reduction in overall hospital length of stay for affected children.
Abstract:
Laparoscopic cholecystectomy (LC) during index hospitalization for gallstone pancreatitis is standard in adult populations. The objective of this study was to evaluate trends in use of LC and endoscopic retrograde cholangiopancreatography (ERCP) for children with gallstone pancreatitis. This retrospective cohort study used the Kids' Inpatient Database, spanning 2000-2019, to identify patients aged 18 years or younger with a principal diagnosis of gallstone pancreatitis. The Mann-Kendall trend test was used to assess trends over time. Gallstone pancreatitis occurred in 5028 patients. The rate of LC during index hospitalization ranged from 55.4% to 63.8% (P = .76). Trends demonstrate that LC occurred on average hospital day 4.6 in 2000 and decreased to 3.4 in 2019 (P < .01). Among those undergoing LC, average length of stay (LOS) decreased from 6.8 days in 2000 to 5.1 days in 2019 (P < .01). The rate of ERCP alone decreased from 24.8% in 2000 to 14.0% in 2019 (P = .23). For those undergoing ERCP, average hospital day of ERCP decreased from 3.3 in 2000 to 2.3 in 2019 (P = .07). The rate of undergoing both an ERCP and LC decreased from 19.0% in 2000 to 8.5% in 2019 (P = .13). For patients who underwent either LC or ERCP, average LOS decreased from 7.0 days in 2000 to 5.1 days in 2019 (P < .01). For patients who did not undergo a procedure, average LOS decreased from 5.7 days in 2000 to 4.0 days in 2019 (P = .13). The proportion of LC performed during index hospitalizations for children with gallstone pancreatitis has been stable for two decades. However, trends indicate that interventions are occurring earlier, and LOS is becoming shorter.
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