68Ga-PSMA-11 PET/CT in a Case of Isolated Parietal Peritoneal Metastasis From Prostate Adenocarcinoma

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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

Published on: January 22, 2018

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Qian Zhao1, Aisheng Dong2, Changjing Zuo2

  • 1From the Department of Nuclear Medicine, General Hospital of Ningxia Medical University, Yinchuan, Ningxia.

Clinical Nuclear Medicine
|September 8, 2023
PubMed

Insights

This study highlights a rare case of prostate cancer spreading to the peritoneum. Gallium-68 PSMA PET/CT imaging proved useful in detecting these unusual peritoneal metastases.

Area of Science:

  • Oncology
  • Nuclear Medicine
  • Radiology

Background:

  • Isolated peritoneal metastasis from prostate cancer is exceptionally rare.
  • Prostate adenocarcinoma can present with atypical metastatic patterns.
  • Gallium-68 PSMA PET/CT is an advanced imaging technique for prostate cancer detection.

Observation:

  • A case of isolated parietal peritoneal metastasis from prostate adenocarcinoma is presented.
  • The metastasis was detected 35 months post-radical prostatectomy.
  • Imaging revealed multifocal intense PSMA uptake in peritoneal lesions with subtle structural changes.

Findings:

  • The peritoneal metastases progressed despite androgen deprivation therapy.
  • Histopathology confirmed metastatic prostate adenocarcinoma with neuroendocrine differentiation.
  • Gallium-68 PSMA PET/CT successfully identified these uncommon metastatic sites.

Implications:

  • This case underscores the utility of Gallium-68 PSMA PET/CT in diagnosing rare prostate cancer presentations.
  • It highlights the potential for treatment-related neuroendocrine differentiation in advanced prostate cancer.
  • Enhanced imaging is crucial for managing atypical metastatic disease.

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