Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Colors and Magnetism03:02

Colors and Magnetism

11.8K
Color in Coordination Complexes
When atoms or molecules absorb light at the proper frequency, their electrons are excited to higher-energy orbitals. For many main group atoms and molecules, the absorbed photons are in the ultraviolet range of the electromagnetic spectrum, which cannot be detected by the human eye. For coordination compounds, the energy difference between the d orbitals often allows photons in the visible range to be absorbed and emitted, which is seen as colors by the human...
11.8K
Electron Transport Chain: Complex III and IV01:43

Electron Transport Chain: Complex III and IV

7.6K
During the electron transport chain, electrons from NADH and FADH2 are first transferred to complexes I and II, respectively. These two complexes then transfer the electrons to ubiquinol, which carries them further to complex III. Complex III passes the electrons across the intermembrane space to Cyt c, which carries them further to complex IV. Complex IV donates electrons to oxygen and reduces it to water. As electrons pass through complexes I, III, and IV, the energy released aids the pumping...
7.6K
Extraction: Advanced Methods00:56

Extraction: Advanced Methods

482
Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is...
482
Metal-Ligand Bonds02:51

Metal-Ligand Bonds

20.9K
The hemoglobin in the blood, the chlorophyll in green plants, vitamin B-12, and the catalyst used in the manufacture of polyethylene all contain coordination compounds. Ions of the metals, especially the transition metals, are likely to form complexes.
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
20.9K
Crystal Field Theory - Octahedral Complexes02:58

Crystal Field Theory - Octahedral Complexes

26.7K
Crystal Field Theory
To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
CFT focuses on...
26.7K
EDTA: Chemistry and Properties01:22

EDTA: Chemistry and Properties

2.0K
Polydentate ligands are most widely used in complexometric titrations because they form more stable complexes with the metal ions than mono- or bidentate ligands due to the chelate effect. Examples of polydentate ligands are ethylenediaminetetraacetic acid (EDTA), crown ethers, and cryptands. The most important feature of optimal polydentate ligands is the ability to form 1:1 complexes in a single-step process. Amino carboxylic acid derivatives are frequently used as complexing agents. EDTA is...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a glutamine-responsive MRI contrast agent.

Chemical science·2025
Same author

Mechanistic Interrogation of a PQQ and Rare Earth-Dependent Artificial Metalloenzyme.

Journal of the American Chemical Society·2025
Same author

Photoelectrochemical Hydride Generation with Oxide-Coated Silicon.

Journal of the American Chemical Society·2025
Same author

Conformational control over proton-coupled electron transfer in metalloenzymes.

Nature reviews. Chemistry·2024
Same author

Periodic Trends in Intra-ionic Excited State Quenching by Halide.

Inorganic chemistry·2024
Same author

Structure-driven development of a biomimetic rare earth artificial metalloprotein.

Proceedings of the National Academy of Sciences of the United States of America·2024

Related Experiment Video

Updated: Jul 17, 2025

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

9.6K

Rapid Electron Transfer Self-Exchange in Conformationally Dynamic Copper Coordination Complexes.

Paul J Griffin1, Lisa Olshansky1

  • 1Department of Chemistry, Center for Biophysics and Quantitative Biology, and Materials Research Laboratory, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|September 8, 2023
PubMed
Summary

We found that dynamic copper complexes with dpa ligands exhibit exceptionally fast electron transfer rates. This conformational flexibility, unlike rigidity in blue copper proteins, is key to efficient electron transfer.

More Related Videos

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

9.2K
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
09:12

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

Published on: May 21, 2019

9.3K

Related Experiment Videos

Last Updated: Jul 17, 2025

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR
14:44

Structure and Coordination Determination of Peptide-metal Complexes Using 1D and 2D 1H NMR

Published on: December 16, 2013

9.6K
Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides
11:04

Ion Mobility-Mass Spectrometry Techniques for Determining the Structure and Mechanisms of Metal Ion Recognition and Redox Activity of Metal Binding Oligopeptides

Published on: September 7, 2019

9.2K
[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
09:12

[DPEPhosbcpCu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst

Published on: May 21, 2019

9.3K

Area of Science:

  • Inorganic Chemistry
  • Bioinorganic Chemistry
  • Physical Chemistry

Background:

  • Electron transfer (ET) is fundamental in biological and chemical systems.
  • Copper complexes are vital catalysts and electron transfer mediators.
  • Understanding factors influencing ET rates is crucial for designing efficient molecular systems.

Purpose of the Study:

  • To investigate the electron transfer self-exchange rate constants (k11) for CuII/I complexes with dpaR ligands.
  • To correlate conformational dynamics of copper complexes with their ET efficiency.
  • To compare the ET properties of these complexes with those of blue copper proteins.

Main Methods:

  • Utilized Nuclear Magnetic Resonance (NMR) line broadening experiments to determine rate constants.
  • Synthesized and characterized copper complexes with dipicolylaniline (dpa) ligands, specifically dpaOMe and dpaSMe.
  • Analyzed the conformational dynamics of the copper complexes in different oxidation states.

Main Results:

  • Reported large k11 values for [CuCl(dpaOMe)]+/0 (2.48 × 10^5 M^-1 s^-1) and [CuCl(dpaSMe)]+/0 (2.21 × 10^6 M^-1 s^-1).
  • The [CuCl(dpaSMe)]+/0 complex exhibits one of the fastest ET rates among molecular copper complexes, comparable to blue copper proteins.
  • Conformational dynamics in the CuI (dpaOMe) or CuII (dpaSMe) complexes led to minimized inner-sphere reorganization energies (0.71 and 0.62 eV, respectively).

Conclusions:

  • Conformational dynamicity in copper complexes, facilitated by dpaR ligands, significantly enhances electron transfer rates.
  • This finding contrasts with the emphasis on rigidity in entatic state models for blue copper proteins.
  • The study highlights the importance of dynamic conformational equilibria in mediating rapid electron transfer in molecular systems.