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A Review of Pediatric Central Line-Associated Bloodstream Infections Reported to the National Healthcare Safety
Christopher Prestel1, Lucy Fike1, Prachi Patel1
1Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Insights
Pediatric central line-associated bloodstream infections (CLABSI) decreased from 2016-2019 but rose between 2019-2022. New prevention strategies are essential to combat these common pediatric healthcare-associated infections.
Area of Science:
- Pediatric healthcare epidemiology
- Infection control and prevention
- Public health surveillance
Background:
- Central line-associated bloodstream infections (CLABSI) represent a significant burden of pediatric healthcare-associated infections.
- Monitoring CLABSI trends is crucial for evaluating the effectiveness of infection control interventions.
Approach:
- Analysis of standardized infection ratios (SIRs) for CLABSI in a pediatric hospital setting.
- Comparison of CLABSI rates during two distinct periods: 2016-2019 and 2019-2022.
Key Points:
- CLABSI SIRs demonstrated a significant decrease of 26% between 2016 and 2019.
- Conversely, CLABSI SIRs showed a significant increase of 18% from 2019 to 2022.
- These trends highlight a concerning reversal in infection control progress.
Conclusions:
- The findings underscore the need for robust and resilient prevention initiatives to address the resurgence of pediatric CLABSI.
- Sustained efforts and innovative strategies are required to regain and maintain reductions in CLABSI rates.
Abstract:
Central line-associated bloodstream infections (CLABSIs) are common healthcare-associated infections in pediatrics. Children's hospital CLABSI standardized infection ratios decreased when comparing 2016-2019 (-26%, 95% CI [-31%, -20%]), and increased from 2019 to 2022 (18%, 95% CI [9%, 26%]). Resilient pediatric CLABSI prevention initiatives are needed.
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