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Related Experiment Video

Updated: Jul 16, 2025

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

The Participant-Reported Implementation Update and Score PRIUS: A Novel Method for Capturing Implementation-Related Data Over Time

Published on: February 19, 2021

Embedding implementation science in the research pipeline.

Leah L Zullig^1,2, Connor Drake^1,2, Devon K Check²

¹Center of Innovation to Accelerate Discovery and Practice Transformation, Durham Veterans Affairs Health Care System, Durham, NC, USA.

Translational Behavioral Medicine

|September 9, 2023

Summary

This summary is machine-generated.

Implementation science can bridge the "valley of death" in healthcare research, accelerating the translation of evidence-based interventions into practice. Embedding these principles ensures scientific discoveries improve patient health more efficiently.

Keywords:

health services methods health services research implementation outcomes implementation science research design translational research

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Area of Science:

Health Services Research
Implementation Science

Background:

Current research paradigms are slow and inefficient for translating discoveries into real-world clinical practice.
A significant gap exists between evidence generation and actual implementation, termed the "valley of death."
Only 14% of evidence-based interventions are implemented, often after 17 years.

Purpose of the Study:

To propose embedding implementation science principles throughout the research pipeline.
To address the challenges of translating scientific discoveries into real-world settings.
To outline implications for capacity building and research design.

Main Methods:

Reviewing current evidence generation and translation paradigms.
Proposing a new research paradigm integrating implementation science.
Identifying necessary components for capacity building in implementation science.

Main Results:

Embedding implementation science can efficiently translate discoveries into real-world contexts.
Capacity building, research team composition, and study design are key implications.
A new research paradigm emphasizes scientists' responsibility for translation.

Conclusions:

Implementation science offers a framework to bridge the gap between research and practice.
Integrating implementation science is crucial for maximizing the impact of health research.
A proactive approach is needed to ensure scientific advancements benefit patient health.