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Updated: Jul 16, 2025

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

Nanobioengineered surface comprising carbon based materials for advanced biosensing and biomedical application.

Ananya Srivastava¹, Uday Pratap Azad²

¹Department of Chemistry, Banaras Hindu University, Varanasi 221005, Uttar Pradesh, India.

International Journal of Biological Macromolecules

|September 10, 2023

Summary

This summary is machine-generated.

Carbon-based nanomaterials (CNMs) offer unique properties for advanced biosensors. This review details CNM classifications, synthesis, and their use in developing ultra-sensitive electrochemical biosensors for early disease diagnosis.

Keywords:

Biosensors Carbon allotropes Carbon nanomaterials Nanobiocomposites Nanobioengineering

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Area of Science:

Materials Science
Nanotechnology
Analytical Chemistry

Background:

Carbon-based nanomaterials (CNMs) are pivotal in materials science due to their unique structures, large surface area, and biocompatibility.
CNMs are increasingly significant in diverse applications including biosensing, bioimaging, and smart drug delivery systems.
Research is ongoing to explore the potential of carbon-based hybrid materials for theranostic and combinatorial therapies.

Approach:

This review focuses on the classification, synthesis, and electroanalytical applications of various CNMs.
It discusses the integration of CNMs with nanomaterials, enzymes, redox mediators, and biomarkers for smart biosensing platforms.
The review highlights the development of efficient and ultra-sensitive electrochemical biosensors for early disease detection.

Key Points:

CNMs exhibit favorable biocompatibility and reactivity, making them ideal for biosensing applications.
Electrochemical biosensors utilizing CNMs enable highly sensitive detection of biomarkers.
The integration of CNMs facilitates the creation of advanced, point-of-care diagnostic tools.

Conclusions:

CNMs are crucial for developing next-generation biosensors with enhanced sensitivity and specificity.
The review provides insights into recent advancements and future prospects of CNMs in biosensing.
This work serves as a valuable resource for researchers in the field of biosensors and diagnostics.